Indoor moulds, Sick Building Syndrome and building related illness

Crook, B.; Burton, Nancy Clark

doi:10.1016/j.fbr.2010.05.001

Cited by 135 publications

(98 citation statements)

References 26 publications

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“…These symptoms may result in affecting the residents' well-beings, or diminishing their productivities rates once they are working. Majority of these symptoms are found to be transient and their effects will be dissipated when the occupants leave the place such as work-related symptoms (Lim et al 2015;Tsai, Lin, and Chan 2012;Zhang et al 2011b), though some of these symptoms can have a long-lasting effects on residents' health namely respiratory-related issues (Crook and Burton 2010;Zhang et al 2012). In order to better understand SBS, the following sections review the major causes of SBS and their negative effects aiming at assisting practitioners to be familiarized with the effects of SBS and its relative symptoms as well as how to mitigate its effect on the occupants.…”

Section: Tssa (2010)mentioning

confidence: 99%

“…They suggested the consideration of preventive strategy designed to mitigate the exposure to indoor chemicals as a solution to counter the occurrence of SBS in newly built houses. Minimizing the interior building products to exterior, decrease the moisture accumulation during construction and striking the balance HVAC systems to control thermal comfort and humidity were among the recommendations given by Crook and Burton (2010) to reduce the possibility for indoor development of mould. Assimakopoulos and Helmis (2004) also found the existence of SBS symptoms among the employees working at the air traffic control tower in Athens.…”

Section: Review Of Studies Mitigating Sbsmentioning

confidence: 99%

“…Crook and Burton (2010) SBS is a complex spectrum of ill health symptoms associated with the indoor environment. In broad terms, these symptoms can be divided into mucous membrane symptoms related to eyes, nose and throat; dry skin; general symptoms of headache and lethargy.…”

Section: Tssa (2010)mentioning

confidence: 99%

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Sick building syndrome: are we doing enough?

AlWaer

Omrany

Ghaffarianhoseini

et al. 2018

Architectural Science Review

178

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Health and well-being are vitally important aspects of people centric building design and are the roots of productivity. Sick building syndrome (SBS) is a collection of factors that can negatively affect physical health in several ways. Besides physical health is also related to psychological well-being because the human body is one interactive biological system. This paper focuses on reviewing the current state of knowledge on building sickness syndrome which has been prevalent as a building illness since the 1970s especially in offices and schools. While the concepts of intelligent, smart and sustainable buildings have gained considerable attention during recent decades, there is now increasing attention being given to designing healthy buildings. This study provides a review about SBS symptoms. Several negative effects of SBS are identified and potential solutions are advocated. Finally, the study stresses the role of built environment and concludes that ongoing research towards tackling SBS and developing healthy indoor environments should not be limited to a single formula as any health-related building design approach is dependent on several interacting factors. ARTICLE HISTORY

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Section: Tssa (2010)mentioning

confidence: 99%

Section: Review Of Studies Mitigating Sbsmentioning

confidence: 99%

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Sick building syndrome: are we doing enough?

AlWaer

Omrany

Ghaffarianhoseini

et al. 2018

Architectural Science Review

178

View full text Add to dashboard Cite

show abstract

“…Samples to test for possible presence of microorganisms, both in air and on surfaces should be taken and measurements of air humidity, temperature and air movement performed. In moderate cases, a thorough cleaning and a ventilation check-up may suffice and in more severe cases large-scale renovation or even demolition of buildings may become necessary [86].…”

Section: Damp and Moldy Buildingsmentioning

confidence: 99%

“…This process occurs parallel to the growth of microorganisms. Buildings affected by the above-mentioned problems are sometimes referred to as sick buildings [86][87].…”

Section: Damp and Moldy Buildingsmentioning

confidence: 99%

Upper Airway Mucosal Inflammation : Proteomic Studies after Exposure to Irritants and Microbial Agents

Fornander¹

2015

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People are, in their daily lives, exposed to a number of airborne foreign compounds that do not normally affect the body. However, depending on the nature of these compounds, dose and duration of exposure, various airway symptoms may arise. Early symptoms are often manifested as upper airway mucosal inflammation which generates changes in protein composition in the airway lining fluid.This thesis aims at identifying, understanding mechanisms and characterizing protein alterations in the upper airway mucosa that can be used as potential new biomarkers for inflammation in the mucosa. The protein composition in the mucosa was studied by sampling of nasal lavage fluid that was further analyzed with a proteomic approach using two-dimensional gel electrophoresis and mass spectrometry. Additionally, by studying factors on site through environmental examination, health questionnaires and biological analyses, we have tried to understand the background to these protein alterations and their impact on health.Respiratory symptoms from the upper airways are common among people who are exposed to irritative and microbial agents. This thesis have focused on personnel in swimming pool facilities exposed to trichloramine, metal industry workers exposed to metalworking fluids, employees working in damp and moldy buildings and infants diagnosed with respiratory syncytial virus infection. The common denominator in these four studies is that the subjects experience upper airway mucosal inflammation, which is manifested as cough, rhinitis, phlegm etc. In the three occupational studies, the symptoms were work related. Notably, a high prevalence of perceived mucosal symptoms was shown despite the relatively low levels of airborne irritants revealed by the environmental examination. Protein profiling verified an ongoing inflammatory response by identification of several proteins that displayed altered levels. Interestingly, innate immune proteins dominated and four protein alterations occurred in most of the studies; SPLUNC1, protein S100A8 and S100A9 and alpha-1-antitrypsin. Similarly, these proteins were also found in nasal fluid from children with virus infection and in addition a truncated form of SPLUNC1 and two other S100 proteins (S100A7-like 2 and S100A16), not previously found in nasal secretion, were identified.Altogether, the results indicate the potential use of a proteomic approach for identifying new biomarkers for the upper respiratory tract at an early stage in the disease process after exposure to irritant and microbial agents. The results indicate an effect on the innate immunity system and the proteins; SPLUNC1, protein S100A8 and S100A9 and alpha-1-antitrypsin are especially promising new biomarkers. Moreover, further studies of these proteins may help us to understand the molecular mechanisms involved in irritant-induced airway inflammation. POPULÄRVETENSKAPLIG SAMMANFATTNING FÖRÄNDRAD PROTEINSAMMANSÄTTNING I DE ÖVRE LUFTVÄGARNA EFTER EXPONERING FÖR SLEMHINNEIRRITERANDE ÄMNENVarje dag utsätts vi för partikla...

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2018

Building Performance Analysis

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Indoor moulds, Sick Building Syndrome and building related illness

Cited by 135 publications

References 26 publications

Sick building syndrome: are we doing enough?

Sick building syndrome: are we doing enough?

Upper Airway Mucosal Inflammation : Proteomic Studies after Exposure to Irritants and Microbial Agents

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