Induced hypertension for preventing complications of delayed cerebral ischaemia in aneurysmal subarachnoid haemorrhage

Haren, Frank Van; Velloza, Peter; Chan, Sean; Mews, Peter; Lueck, Christian J.

doi:10.1002/14651858.cd012842

Cited by 1 publication

(2 citation statements)

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“… 11 This may be done after the aneurysm has been treated with either open surgery or endovascular therapy. 15 There are also numerous examples in the literature supporting the use of IH even in unsecured aneurysms, wherein no clipping or coiling has been done. These studies suggest that IH does not significantly increase the risk of rupture of additional unsecured aneurysms.…”

Section: Introductionmentioning

confidence: 99%

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The effect of induced hypertension in aneurysmal subarachnoid hemorrhage: A narrative review

Azari Jafari,

Mirmoeeni,

Johnson

et al. 2023

CJN

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Aneurysmal subarachnoid hemorrhage ‎(aSAH) ‎accounts for 2-5% of all strokes, and 10%‐15% of ‎aSAH patients will not survive until hospital admission. Induced hypertension (IH) is an emerging therapeutic option being used for the treatment of vasospasm in ‎aSAH. For patients with cerebral vasospasm (CVS) consequent to SAH, IH is implemented to increase systolic blood pressure (SBP) in order to optimize cerebral blood flow (CBF) and prevent delayed cerebral ischemia (DCI). Prophylactic use of IH has been associated with the development of vasospasm and cerebral ischemia in SAH patients. Various trials have defined several different parameters to help clinicians decide when to initiate IH in a SAH patient. However, there is insufficient evidence to recommend therapeutic IH in aSAH due to the possible serious complications like myocardial ischemia, development of posterior reversible encephalopathy syndrome (PRES), pulmonary edema, and even rupture of another unsecured aneurysm. This narrative review showed the favorable impact of IH therapy on aSAH patients; however, it is crucial to conduct further clinical and molecular experiments to shed more light on the effects of IH in aSAH.

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Section: Introductionmentioning

confidence: 99%

“… 16 This intervention involves the administration of vasoactive agents, such as catecholamines (norepinephrine, dobutamine, and dopamine), phenylephrine, along with the standard calcium channel antagonists (nimodipine). 15 , 17 …”

Section: Introductionmentioning

confidence: 99%

The effect of induced hypertension in aneurysmal subarachnoid hemorrhage: A narrative review

Azari Jafari,

Mirmoeeni,

Johnson

et al. 2023

CJN

View full text Add to dashboard Cite

show abstract

Induced hypertension for preventing complications of delayed cerebral ischaemia in aneurysmal subarachnoid haemorrhage

Abstract: 11. Art. No.: CD012842. Cochrane Reviews are regularly updated as new evidence emerges and in response to comments and criticisms, and the Cochrane Database of Systematic Reviews should be consulted for the most recent version of the Review.

Cited by 1 publication

References 15 publications

The effect of induced hypertension in aneurysmal subarachnoid hemorrhage: A narrative review

The effect of induced hypertension in aneurysmal subarachnoid hemorrhage: A narrative review

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