In view of characteristics of involute helical gear profile, analyzed the multi-axis machining process for helical gear. Focused on the processing characteristics of helical gear for multi-axis machining, discussed tool path generation, machining program, tool path simulation, cutter interference and collision detection for machine tool and gear profile, seeking out the optimal method and process of helical gear for multi-axis machining. Applying this machining technology in manufacture, it can improve performance of gear, while it can also improve efficiency of manufacture.