Induction of innate immune response in whiteleg shrimp (Litopenaeus vannamei) embryos

Alvarez-Lee, Angélica; Martínez-Díaz, Sergio F.; Gutiérrez‐Rivera, Jesús Neftalí; Lanz‐Mendoza, Humberto

doi:10.1016/j.dci.2019.103577

Cited by 12 publications

(6 citation statements)

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“…HIF-1 silencing in WSSV-infected shrimps blocks the upregulation of the glycolytic enzymes HK, PFK and PK and the expression and activity of LDH, increasing survival of the infected animals. 132 Immune training or priming using heat-killed pathogens, heat shock proteins or poly(I.C) mimicking double-stranded viral RNA can trigger strong effector immune responses in invertebrates 53,55,[133][134][135] and knowledge about specific gene products with potential high efficacy for immune priming resulting in disease resistance is needed.…”

Section: Immune and Cellular Response To Infection And Infestationmentioning

confidence: 99%

“…52 Despite the lack of an adaptive immune system, stimulation of the innate immune system of shrimp by immune priming shows promise but has not yet been proven to prevent and control disease in the field. [53][54][55] These two infectious diseases have a large impact on these aquaculture sectors, but similar disease problems affect all aquaculture species with devastating consequences. 56,57 Alternative measures for preventing infestation and infection are needed.…”

Section: Introductionmentioning

confidence: 99%

“…Elimination of the virus from the open pond systems in which shrimp are extensively grown has not been possible 52 . Despite the lack of an adaptive immune system, stimulation of the innate immune system of shrimp by immune priming shows promise but has not yet been proven to prevent and control disease in the field 53–55 …”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Applying genetic technologies to combat infectious diseases in aquaculture

Robinson

Robledo

Sveen

et al. 2022

Reviews in Aquaculture

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Disease and parasitism cause major welfare, environmental and economic concerns for global aquaculture. In this review, we examine the status and potential of technologies that exploit genetic variation in host resistance to tackle this problem. We argue that there is an urgent need to improve understanding of the genetic mechanisms involved, leading to the development of tools that can be applied to boost host

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Section: Immune and Cellular Response To Infection And Infestationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Applying genetic technologies to combat infectious diseases in aquaculture

Robinson

Robledo

Sveen

et al. 2022

Reviews in Aquaculture

View full text Add to dashboard Cite

show abstract

“…Whereas crustaceans generally carry their eggs with them and make a large maternal investment [77], the serosal cells are of zygotic origin. Crustacean eggs have been reported to upregulate immune genes upon infection, but this upregulation seems to be rather weak (less than fourfold upon infection maximally) and shortly before hatching [78]. The serosa has allowed insects to lay desiccation resistant and strongly immune competent eggs, probably relieving the need for parental care.…”

Section: Discussionmentioning

confidence: 99%

Immune function of the serosa in hemimetabolous insect eggs

Jacobs

Hulst

Chen

et al. 2022

Phil. Trans. R. Soc. B

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Insects comprise more than a million species and many authors have attempted to explain this success by evolutionary innovations. A much overlooked evolutionary novelty of insects is the serosa, an extraembryonic epithelium around the yolk and embryo. We have shown previously that this epithelium provides innate immune protection to eggs of the beetle Tribolium castaneum. It remained elusive, however, whether this immune competence evolved in the Tribolium lineage or is ancestral to all insects. Here, we expand our studies to two hemimetabolous insects, the bug Oncopeltus fasciatus and the swarming grasshopper Locusta migratoria . For Oncopeltus , RNA sequencing reveals an extensive response upon infection, including the massive upregulation of antimicrobial peptides (AMPs). We demonstrate antimicrobial activity of these peptides using in vitro bacterial growth assays and describe two novel AMP families called Serosins and Ovicins. For both insects, quantitative polymerase chain reaction shows immune competence of the eggs when the serosa is present, and in situ hybridizations demonstrate that immune gene expression is localized in the serosa. This first evidence from hemimetabolous insect eggs suggests that immune competence is an ancestral property of the serosa. The evolutionary origin of the serosa with its immune function might have facilitated the spectacular radiation of the insects. This article is part of the theme issue ‘Extraembryonic tissues: exploring concepts, definitions and functions across the animal kingdom’.

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Antimicrobial activity of PvH4a, a peptide derived from histone H4 of Penaeus vannamei

Shen

Aweya

et al. 2022

Aquaculture

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Induction of innate immune response in whiteleg shrimp (Litopenaeus vannamei) embryos

Cited by 12 publications

References 50 publications

Applying genetic technologies to combat infectious diseases in aquaculture

Applying genetic technologies to combat infectious diseases in aquaculture

Immune function of the serosa in hemimetabolous insect eggs

Antimicrobial activity of PvH4a, a peptide derived from histone H4 of Penaeus vannamei

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