AIM:The aim of this study was to compare the efficacy of extra amniotic Foleys catheter and intra cervical PGE2 gel in cervical ripening for the successful induction of labor. STUDY DESIGN: A randomized, prospective study was conducted in the Dept. of OBGY, KIMS, Karad from May 2012 to May 2014. 140 patients at term with a Bishop's score <6 with various indications for induction were randomly allocated to receive (70 pts) extra amniotic Foleys catheter or PGE2 gel (70 pts). After 6 h post induction, Bishop's score was noted labor was augmented if required. Statistical analysis was done using Chi square test and t test. RESULT: The groups were compared with respect to maternal age, gestation age, indication of induction and initial Bishop's score. Both the groups showed no significant change in the Bishop's score for primigravida cases (P value-0.6) but for multigravida cases increment in Bishop's score was significantly more for PGE2 group (P value-0.048). There was no significant difference in the side effects For primigravida cases there was no significant difference in cesarean section rate for both groups but in multigravida cases cesarean section rate significantly more in Foleys group (P value-0.049).There was no significant difference in the induction to delivery interval in both groups for primigravida cases, but for multigravida cases duration was significantly less in PGE2 group (P value-0.047). APGAR scores and NICU admissions showed no difference between the two groups. Cost of induction was significantly less for Foleys catheter than PGE2 gel. CONCLUSION: This study shows that both Foleys Catheter and PGE2 gel were equally effective in pre induction cervical ripening in primigravida cases but for multigravida cases PGE2 gel was more effective than Foleys catheter for pre induction cervical ripening. KEYWORDS: Cervical ripening, PGE2, Foleys catheter.
INTRODUCTION:Cervical ripening refers to a process of preparing the cervix for induction of labor by promoting effacement and dilatation as measured by Bishop's score. The success of labor induction depends on the cervical status at the time of induction. It is generally predicted that the patients with a poor Bishop's score <3 have unacceptably higher rates of failure of induction. It was also shown that a low Bishop's score is associated with increased rates of cesarean sections, maternal fever and fetal asphyxia. To decrease the induction failure, cervical ripening by any methods is the answer.The purpose of this study was to compare the efficacy of extra amniotic Foleys catheter with PGE2 gel for pre-induction cervical ripening. The induction delivery interval, maternal and fetal outcomes and the need for augmentation of labor in or these two groups were also compared.