Induction of Labor by Oxytocin or Prostaglandin E<sub>2</sub>

Bremme, Katarina; Bygdeman, M.

doi:10.3109/00016348009156933

Cited by 10 publications

(2 citation statements)

References 43 publications

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“…In general the two treatment groups did not differ significantly but nulliparous women were somewhat more common in the prostaglandin group and patients with a low Bishop's score were significantly more frequent in the oxytocin group. The two treatments were equally effective; 91 per cent of the patients delivered vaginally within 24 hours after the start of therapy (10).…”

Section: Amniotomy and Rnrnhgmentioning

confidence: 96%

A Comparative Study of Uterine Activity and Fetal Heart Rate Pattern in Labor Induced with Oral Prostaglandin E₂ or Oxytocin

Bremme

Bygdeman

1980

Acta Obstet Gynecol Scand

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Section: Amniotomy and Rnrnhgmentioning

confidence: 96%

A Comparative Study of Uterine Activity and Fetal Heart Rate Pattern in Labor Induced with Oral Prostaglandin E₂ or Oxytocin

Bremme

Bygdeman

1980

Acta Obstet Gynecol Scand

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“…Various investigations carried out over the last 10 years have demonstrated that oral prostaglandin E2 (PGE3 is just as effective as intravenous oxytocin for this purpose (2,5,11,13).…”

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confidence: 99%

Oral Oxytocics for Induction of Labor

Westergaard

Lange

Pedersen

et al. 1983

Acta Obstet Gynecol Scand

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A randomized comparative study of 387 consecutive patients admitted for induction of labor was carried out using two orally administered oxytocics (prostaglandin E2 tablets (Prostin) or Demoxytocin resoriblets for buccal administration (Sandopart)), the results of which are reported here. One-hundred and twenty-three cases were suitable for primary amniotomy; of these 48 were given PGE2 tablets and 75 received demoxytocin resoriblets. In a further 264 cases, primary amniotomy was inadvisable and of these, 133 patients were allotted to the PGE2 treatment group and 131 to treatment with demoxytocin. A significantly higher success rate was observed (p less than 0.05) in the PGE2 group in cases where primary amniotomy had been carried out, as compared with the demoxytocin group. Parturition was successfully induced in 82.0% of the patients given PGE2 tablets, as against only 63.4% of those receiving demoxytocin following 2 days of stimulation without primary amniotomy. This difference is statistically significant at the 0.001 level, and presumably due to the highly significant difference (p less than 0.0001) between patients with a Bishop score of 5 or less, where induction was successful in 75.4% given PGE2 tablets, in contrast to a success rate of only 36.7% in patients receiving demoxytocin resoriblets. No difference was observed in the success rate between the two treatment groups when the Bishop score was 6 or more. No difference was recorded in the incidence of fetal distress, instrumental delivery or low Apgar score between the two treatment groups. However, a higher incidence of vomiting and diarrhea were observed in patients treated with PGE2 tablets (11%) as compared with those receiving demoxytocin (1.5%). There was no difference with regard to the induction-delivery time, nor to the different stages of labor between otherwise comparable treatment groups when the induction was successful. It is concluded in respect of induction of labor using orally administered oxytocics that PGE2 (tablets) are preferable to demoxytocin (resoriblets) as it is the more effective of the two.

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Retinal Hemorrhages in the Newborn Following Labor Induced by Oxytocin or Dinoprostone

Schoenfeld¹,

Buckman²,

Nissenkorn³

et al. 1985

Archives of Ophthalmology

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Induction of Labor by Oxytocin or Prostaglandin E₂

Abstract: The efficacy and safety of oral PGE, or intravenous infusion of oxytocin, in both cases combined with early amniotomy, for induction of labor on medical grounds, were compared in a randomized study of 200 women. After an initial dose of 0.5 mg, 1.0 mg of PGE, was

Cited by 10 publications

References 43 publications

A Comparative Study of Uterine Activity and Fetal Heart Rate Pattern in Labor Induced with Oral Prostaglandin E₂ or Oxytocin

A Comparative Study of Uterine Activity and Fetal Heart Rate Pattern in Labor Induced with Oral Prostaglandin E₂ or Oxytocin

Oral Oxytocics for Induction of Labor

Retinal Hemorrhages in the Newborn Following Labor Induced by Oxytocin or Dinoprostone

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Induction of Labor by Oxytocin or Prostaglandin E2

Abstract: The efficacy and safety of oral PGE, or intravenous infusion of oxytocin, in both cases combined with early amniotomy, for induction of labor on medical grounds, were compared in a randomized study of 200 women. After an initial dose of 0.5 mg, 1.0 mg of PGE, was

Cited by 10 publications

References 43 publications

A Comparative Study of Uterine Activity and Fetal Heart Rate Pattern in Labor Induced with Oral Prostaglandin E2 or Oxytocin

A Comparative Study of Uterine Activity and Fetal Heart Rate Pattern in Labor Induced with Oral Prostaglandin E2 or Oxytocin

Oral Oxytocics for Induction of Labor

Retinal Hemorrhages in the Newborn Following Labor Induced by Oxytocin or Dinoprostone

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Induction of Labor by Oxytocin or Prostaglandin E₂

A Comparative Study of Uterine Activity and Fetal Heart Rate Pattern in Labor Induced with Oral Prostaglandin E₂ or Oxytocin

A Comparative Study of Uterine Activity and Fetal Heart Rate Pattern in Labor Induced with Oral Prostaglandin E₂ or Oxytocin