Induction therapy for Stage III NSCLC: A consensus report

Radical Treatment of Non–Small-Cell Lung Cancer Patients with Synchronous Oligometastases: Long-Term Results of a Prospective Phase II Trial (Nct01282450)

“…Local tumor control of all radical treated locations (both the primary tumor and the metastases) was evaluated according to the criteria of Green 33 after radiotherapy and according to Response Evaluation Criteria In Solid Tumors for nonirradiated sites. 34 Tumor progression was scored when one or both occurred.…”

Continuous hyperfractionated accelerated radiation therapy week-end less in combination with neoadjuvant chemotherapy for the treatment of stage III non-small-cell lung cancer

“…Locoregional recurrence was defined as evidence of tumor progression and/or enlargement of mediastinal lymph nodes included in PTV or recurrence of disease in an initially uninvolved mediastinal lymph node located outside of the PTV. Complete response following CHARTWEL was defined according to standard criteria [21]. Thus, patients showing complete disappearance of any malignant disease or residual radiographic abnormalities on chest CT at 3 and 6 months after completion of radiotherapy, which remains stable for at least 6 additional months, were classified as having controlled local disease.…”

Incorporation of photodynamic therapy as an induction modality in non-small cell lung cancer

“…Gross inspection at the time of rigid bronchoscopic assessment revealed an objective reduction in the tumor mass with amelioration of an occlusive growth pattern in the bronchus while pathologically; tumor cell necrosis was observed (Figs. [2][3][4][5].…”

“…Adjunctive preoperative modalities are frequently undertaken so that a potentially unresectable tumor is rendered surgically treatable and/or there is a sufficient reduction in tumor burden to allow a lesser resection with associated enhanced preservation of lung function. Chemotherapy combined with radiation therapy define the most common modalities of induction therapy [4][5][6].…”