Induktion der Spermiogenese nach antegrader Varikozelensklerosierung bei Patienten mit nicht-obstruktiver Azoospermie

Horst, C. van der; Weyel, T.; Danilevičius, Mindaugas; Braun, P.; Alken, P.; Jünemann, K. P.; Portillo, F. J. Martínez

doi:10.1055/s-2005-915619

Cited by 4 publications

(2 citation statements)

References 7 publications

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“…This is to avoid sperm retrieval by testis tissue extraction (TESE) and the associated injury to the testicular parenchyma. This effect has already been demonstrated for percutaneous varicocele embolization [18]. Even if no spermatozoa are detected in the ejaculate postoperatively, the probability of successful TESE may be increased.…”

Section: Laparoscopic Varicocelectomy In Male Infertility Original Articlementioning

confidence: 78%

Laparoscopic varicocelectomy in male infertility

Seiler

Kneissl

Hamann

et al. 2021

Wien Klin Wochenschr

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Summary Background The suitability of laparoscopic varicocelectomy for assisted reproductive technology depends on the improvement of semen parameters. The present study analyzed the improvement of semen parameters following laparoscopic varicocele ligation. Material and methods A retrospective study of the laparoscopic varicocele clippings at the Department of Urology of University Hospital of Kiel between the years 2007 and 2019 was conducted. The semen analyses according to WHO standards (sperm count, density, motility and morphology) were conducted before and 12 months after surgery. Screening for surgical complications took place at the time of the follow-up seminal analysis. Included were patients with oligozoospermia, asthenozoospermia and/or teratozoospermia (group 1, OAT) or with nonobstructive azoospermia (group 2, NOA). Results This study included data of 27 patients and 22 patients presented preoperative OAT (81%, group 1). Another 5 patients showed NOA (19%, group 2). Data of group 1 showed that semen parameters normalized in 32% of the patients after surgery. Significant improvement in total sperm count (p < 0.005), sperm density (p < 0.005) and total motile sperm count (p < 0.005) was observed. No deterioration of semen parameters was observed. In group 2 we detected spermatozoa in 1 case in the postoperative ejaculate. None of the patients showed complications according to the Clavien-Dindo classification, postoperative hydrocele formation or recurrence of varicocele at the time of control spermiogram. Conclusion Laparoscopic varicocelectomy is a valid therapeutic approach to improve semen parameters for further assisted reproductive techniques. Spermatogenesis may be induced for patients with NOA. Normalization of semen parameters can be achieved for patients with OAT.

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Section: Laparoscopic Varicocelectomy In Male Infertility Original Articlementioning

confidence: 78%

Laparoscopic varicocelectomy in male infertility

Seiler

Kneissl

Hamann

et al. 2021

Wien Klin Wochenschr

View full text Add to dashboard Cite

show abstract

“…ASS is regularly used as an outpatient treatment under local anaesthesia, and takes 15–20 min. The treatment results in low persistence rates of 9% in adults [4,5] and 3% in children, respectively [6,7]; an improvement in sperm count according to the WHO criteria [3,8], even in men with unobstructive azoospermia [9]; and a paternity rate of 42%[8].…”

Section: Resultsmentioning

confidence: 99%

Surgical Atlas Varicocele: antegrade scrotal sclerotherapy

Tauber

Pfeiffer

2006

BJU International

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The role of varicocele sclerotherapy in men with severe oligo-astheno-teratozoospermia

Ghanem¹,

Safan²,

Ghanem³

et al. 2011

Asian J Androl

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The aim of this study was to verify the role of antegrade scrotal sclerotherapy for the treatment of varicoceles in infertile men with severe oligo-astheno-teratozoospermia (OAT). The 59 patients with severe OAT in this study underwent antegrade scrotal sclerotherapy for the treatment of varicoceles. The outcome was assessed in terms of improvement in semen parameters and spontaneous conception rate. Semen parameters and reproductive hormones were evaluated before antegrade sclerotherapy (AS) and 6 months after AS. After an average follow-up time of 34.863.2 months, significant improvement was noted in the mean sperm concentration, motility and morphology in 36 patients (61%). Spontaneous pregnancy occurred in nine couples (15%). Six months after treatment, inhibin B levels were significantly higher (P,0.04), whereas follicle-stimulating hormone (FSH) levels were significantly lower (P,0.001) than before treatment. Antegrade internal spermatic vein sclerotherapy can significantly improve seminal parameters and hormonal parameters in men with severe OAT and may even result in spontaneous pregnancy in couples who would otherwise be candidates for intracytoplasmic sperm injection (ICSI). 1 Several studies have confirmed an association between varicocele and testicular dysfunction, reflected by abnormal semen and the loss of testicular volume.

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Induktion der Spermiogenese nach antegrader Varikozelensklerosierung bei Patienten mit nicht-obstruktiver Azoospermie

Cited by 4 publications

References 7 publications

Laparoscopic varicocelectomy in male infertility

Laparoscopic varicocelectomy in male infertility

Surgical Atlas Varicocele: antegrade scrotal sclerotherapy

The role of varicocele sclerotherapy in men with severe oligo-astheno-teratozoospermia

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Induktion der Spermiogenese nach antegrader Varikozelensklerosierung bei Patienten mit nicht-obstruktiver Azoospermie

Cited by 4 publications

References 7 publications

Laparoscopic varicocelectomy in male infertility

Laparoscopic varicocelectomy in male infertility

Surgical Atlas Varicocele: antegrade scrotal sclerotherapy

The role of varicocele sclerotherapy in men with severe oligo-astheno-teratozoospermia

Contact Info

Product

Resources

About

Surgical Atlas Varicocele: antegrade scrotal sclerotherapy