Objective-An epidemiological investigation to assess the validity of residential proximity to industry as a measure of community exposure.
Methods-19Housing estates in Teesside (population 1991: 77 330) in north east England were grouped into zones: A=near; B=intermediate; C=further from industry. With residential proximity of socioeconomically matched populations as a starting point a historical land use survey, historical air quality reports, air quality monitoring, dispersion modelling data, and questionnaire data, were examined. Results-The populations in zones A, B, and C were similar for socioeconomic indicators and smoking history. Areas currently closest to industry had also been closest for most of the 20th century. Historical reports highlighted the influence of industrial emissions to local air quality, but it was diYcult to follow spatial pollution patterns over time. Whereas contemporary NO x and benzene concentrations showed no geographical variation, dispersion modelling of emissions (116 industrial stacks, traYc, and domestic sources) showed a gradient associated with industry. The presumed exposure gradient of areas by proximity to industry (A>B>C) was evident for all of zone A and most of zones B and C. Conclusions-It was feasible to assemble a picture of community exposure by integration of measurements from diVerent sources. Proximity of residence was a reasonable surrogate for complex community exposure. (Occup Environ Med 2000;57:542-549) Keywords: exposure assessment; community exposure; industrial pollutionIn environmental epidemiology studies the assessment of exposure of a population remains both an on going area of concern when interpreting results and a major methodological challenge at the design stage. This is especially the case for retrospective exposure assessment: gaps in the spatial and temporal coverage, the relative crudity of past measurement techniques, and changes in techniques are among the many problems; and exposure assessment has therefore been earmarked as an area of future research. To analyse the associations between exposure to industrial air pollution and the health of residents living close to industries a comprehensive picture of past and contemporary exposure is required. However, to characterise air pollution and its variability in time and space, necessitates reliance largely on data collected for diVerent purposes-for example, to fulfil statutory obligations. In the end, a judgement has to be made on how far the chosen exposure measures are likely to reflect the exposure of the population.Based on the study of detailed accounts of the validity and reliability of exposure measurements and a systematic analysis of diVerential misclassification of exposure, 2-6 the criteria we used to make judgements on whether the exposure surrogate residential proximity to industry was valid were: (a) Have we been able to characterise the temporal and spatial pattern of exposure in our study areas? (b) Have we been able to disentangle industrial sources from other ...