After years of research, it can be stated that graphene was an initial game changer and jack of all trades in the world of nanotechnology, owing to innumerable structural/physical characteristics and mammoth range of hi-tech applications. Undoubtedly, since the discovery of graphene, it almost ruled all possible nanotechnological fields, from electronics/energy—to—defense/transportation/civil—to—biomedical. Nevertheless, this statement remained no longer valid after the discovery of more erudite nanostructures, like fullerene, quantum dots, and similar nanoparticles. Reasons for today’s technology turns towards tiny symmetrical nanoparticles seem to be the limitations/hinderance for integrating graphene into energy/semiconducting/photonic devices, and subsequent commercialization over past two decades. In this novel perspective report, therefore, we first time critically analyzed the nanotechnological shifts from graphene, yet despite its early promises, towards proficient zero dimensional entities.