Sugar production is essential for the production of foods, biochemicals, and biofuels via biochemical or catalytic routes. Sugar‐containing crops, and starch‐based and cellulosic feedstocks are resources for sugar production via juice extraction, starch saccharification, and pretreatment and hydrolysis, respectively. Technologies have been developed to attain a high sugar yield; however, production costs are a major consideration in commercializing newly developed approaches to the production of sugars. In this review, the fixed capital and production costs of sugar produced from first‐ and second‐generation crops are summarized. As expected, first‐generation crops provide the lowest fixed capital costs, ranging from 0.01 to 0.13 $ kg−1 feedstock, and have production costs ranging from 0.22 to 0.55 $ kg−1 sugar. For cellulosic crops, because of their recalcitrant structure and complex processing, the fixed capital and production costs are higher, ranging from 0.02 to 1.10 $ kg−1 feedstock and 0.10 to 3.37 $ kg−1 sugar, respectively. © 2019 Society of Chemical Industry and John Wiley & Sons, Ltd.