Education informatization uses intelligent algorithms and information technology to develop educational resources, optimize the educational process, and establish a modern education concept. The global education system is the general term for the education system of different countries and regions. There are internal connections but also significant differences. Education informatization can reuse the educational resources of developed countries, improve the education level of developing countries, and realize the undifferentiated development of global education. The research on education informatization mainly stays at the theoretical level and lacks the optimization technology of the educational process, which limits the sustainable development of the global education system. Therefore, this paper proposes a global education system optimization method based on information technology, which classifies educational resources, concepts and processes in different regions and countries. Then, the system education is built through the B/S framework, and the educational resources of different B/S layers are transmitted through the wireless transmission protocol to complete the construction of the global education system. Finally, the global education system is evaluated. The results show that the global education system optimization method proposed in this paper can improve the sustainability of educational resources, the optimization rate of educational resources is greater than 80%, the optimization accuracy of the educational process is greater than 90%, and the improvement rate of educational philosophy is greater than 80%., significantly higher than the previous network information platform. Therefore, this paper proposes that the wireless transmission protocol can support education informatization, promote the sustainable development of the global education system, promote the balance of educational resources in different countries and regions, and enhance the modern education concept.