Industrially synthesized biosafe vaterite hollow CaCO3 for controllable delivery of anticancer drugs

Calcium Carbonate-Based Nanoplatforms for Cancer Therapeutics: Current State of Art and Future Breakthroughs

“…CaCO 3 NPs can load both hydrophobic and hydrophilic molecules (such as chemotherapy drugs, nucleic acids and other functional molecules), making them suitable carriers for chemotherapy, gene therapy, photodynamic therapy (PDT), etc . For example, Feng et al developed a simple, rapid, and controllable industrial method to synthesize high-drug-loaded vaterite hollow calcium carbonate (VHC) . In the industrial preparation of CaCO 3 , VHC can be prepared by using l -leucine.…”

3D Printed Gas Distributor for Enhanced Production of CaCO3 via Bubbling Carbonation

“…Moreover, the fluid shear caused by vortex and bubble motion can cause abrasion and secondary nucleation of the growing crystals, which in turn affects the morphology and size distribution of the calcium carbonate product. Stirring may break the CaCO 3 crystals with the formation of irregular aggregates . The CO 2 injection method and the flow rate of CO 2 significantly also affect the size of the primary calcite particles in a microbubble carbonation reactor. , These reported studies suggested that the size distribution of CO 2 bubbles has remarkable effects on the size and morphology of the CaCO 3 product.…”

“…Stirring may break the CaCO 3 crystals with the formation of irregular aggregates. 33 The CO 2 injection method and the flow rate of CO 2 significantly also affect the size of the primary calcite particles in a microbubble carbonation reactor. 34 , 35 These reported studies suggested that the size distribution of CO 2 bubbles has remarkable effects on the size and morphology of the CaCO 3 product.…”

Probing capping mechanisms and polymer matrix loading of biogenic vaterite CaCO3–Ag hybrid through X-ray photoelectron spectroscopy (XPS)

“…7 Introducing vectors or carriers, such as vaterite calcium carbonate (CaCO 3 ), present a signicant solution to these challenges. [8][9][10][11] By utilizing vaterite CaCO 3 , the stability issues of AgNPs can be effectively mitigated, enhancing their overall potential. However, to fully harness the benets of this approach, it is essential to comprehend the interactions between AgNPs and CaCO 3 , as well as their behaviour aer loading into diverse polymer matrices.…”