This chapter provides a questionnaire-based survey on individuals, with an attempt to examine general awareness about I4.0, in the South India region. Results show inadequate future expectations regarding effects on several aspects of respondents’ lives, which mostly stem from a rather poor informational level of I4.0. Conversely, rather positive opinions and expectations of possible future trends come from respondents with prior information about I4.0. Thus, from a broader discussion we generalize, that for sustainable and successful development leading towards the Fourth Industrial Revolution, sufficient information and knowledge base within the potential labour force, especially in a particular region with promising demography, should be achieved. We find obtained information not negligible from SMEs management perspective and successful development of organization and network models.