INECO Frontal Screening (IFS): A brief, sensitive, and specific tool to assess executive functions in dementia – ERRATUM

Torralva, Teresa; Roca, María; Gleichgerrcht, Ezequiel; López, Pablo; Manes, Facundo

doi:10.1017/s1355617710000883

Cited by 46 publications

(91 citation statements)

References 41 publications

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“…Therefore, a proper screening battery of tests that seeks to differentiate AD from vascular dementia should address this fact and therefore include measures not only of episodic memory, but also of executive functions. In this sense, the addition of a screening tool such as the INECO Frontal Screening [27] could improve the discriminatory capacity of screening tools. The IFS is a brief, sensitive, and specific tool for the detection of executive dysfunction and we have recently showed this test is more sensitive and specific in differencing bvFTD from AD in comparison to Frontal Assessment Battery (FAB) [28], which is probably one of the most extensively used screening tools that has been design to specially asses executive functions [29][30][31][32].…”

Section: Discussionmentioning

confidence: 99%

The Spanish version of the Addenbrooke's Cognitive Examination — Revised (ACE-R) in subcortical ischemic vascular dementia

Raimondi

Gleichgerrcht

Richly

et al. 2012

Journal of the Neurological Sciences

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Section: Discussionmentioning

confidence: 99%

The Spanish version of the Addenbrooke's Cognitive Examination — Revised (ACE-R) in subcortical ischemic vascular dementia

Raimondi

Gleichgerrcht

Richly

et al. 2012

Journal of the Neurological Sciences

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“…Several studies have demonstrated the usefulness of one screening tool specifically designed to probe executive functions: the IFS [22,26,27,29]. Here, we examine the properties of the IFS as an executive screening test for patients with RRMS.…”

Section: Discussionmentioning

confidence: 99%

“…All participants were assessed with the WAT-BA [31] as a test of premorbid intelligence (similar to the NART [32]), as well as with the IFS [22] and a classical executive battery.…”

Section: Neuropsychological Assessmentmentioning

confidence: 99%

“…Several such executive screening tests have been designed, including the Frontal assessment battery (FAB) [21]; the INECO frontal screening (IFS) [22] and the verbal fluency test [23]. Results using these tests have been mixed.…”

Section: Introductionmentioning

confidence: 99%

“…It has also been shown useful in the detection of executive dysfunction in other neurological and psychiatric conditions such as unipolar depression [26], bipolar disorder, and attentional and hyperactivity disorder [27]. Several studies have already reported on the usefulness of this instrument in different populations, reporting relatively high levels of specificity and sensitivity for a screening tool [22], along with a higher ability than other executive screening tools to discriminate between different types of dementia [28], between dementia and depression [26], and to detect executive dysfunction in patients with attention deficit disorder [21,29]. However, no previous study has investigated its utility in detecting executive dysfunction in patients with MS, who as stated above, tend to primarily and very frequently show this form of cognitive impairment.…”

Section: Introductionmentioning

confidence: 99%

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Utility of the INECO frontal screening (IFS) in the detection of executive dysfunction in patients with relapsing-remitting multiple sclerosis (RRMS)

et al. 2015

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Several studies have reported that about 65 % of patients with relapsing-remitting multiple sclerosis (RRMS) suffer from cognitive impairment, with executive dysfunction being the most frequently described. Even if several executive screening tests have been designed to specifically detect executive deficits, few studies have investigated their ability to tackle such dysfunction particularly in multiple sclerosis (MS). The aim of the present study was to evaluate the sensitivity and specificity of the INECO frontal screening (IFS) in the detection of executive dysfunction in patients with relapsing-remitting MS (RRMS). 54 patients with RRMS were included in the study. 34 presented executive dysfunction while 20 did not. 32 control subjects matched for age, sex, and educational level were also included. All were evaluated with the IFS and with a battery of classical executive tests. A patient was considered to have executive dysfunction if he/she scored a one and a half standard deviation below the control mean in at least one of the classical executive tests. Sensitivity and specificity of the IFS in its ability to detect executive dysfunction in MS was analyzed. Using a cut-off of 25.5 points, sensitivity of the IFS was 73.53 %, and specificity 78.13 % in differentiating controls from MS patients with executive dysfunction. The IFS showed excellent concurrent validity with executive tasks. The IFS can be considered a brief, easy-to-administer, cost-less tool for the detection of executive dysfunction in patients with RRMS.

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Structural neuroimaging differentiates vulnerability from disease manifestation in colombian families with Huntington's disease

et al. 2019

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Introduction The volume of the striatal structures has been associated with disease progression in individuals with Huntington's disease (HD) from North America, Europe, and Australia. However, it is not known whether the gray matter (GM) volume in the striatum is also sensitive in differentiating vulnerability from disease manifestation in HD families from a South‐American region known to have high incidence of the disease. In addition, the association of enlarged brain perivascular spaces (PVS) with cognitive, behavioral, and motor symptoms of HD is unknown. Materials and Methods We have analyzed neuroimaging indicators of global atrophy, PVS burden, and GM tissue volume in the basal ganglia and thalami, in relation to behavioral, motor, and cognitive scores, in 15 HD patients with overt disease manifestation and 14 first‐degree relatives not genetically tested, which represent a vulnerable group, from the region of Magdalena, Colombia. Results Poor fluid intelligence as per the Raven's Standard Progressive Matrices was associated with global brain atrophy ( p = 0.002) and PVS burden ( p ≤ 0.02) in HD patients, where the GM volume in all subcortical structures, with the exception of the right globus pallidus, was associated with motor or cognitive scores. Only the GM volume in the right putamen was associated with envy and MOCA scores ( p = 0.008 and 0.015 respectively) in first‐degree relatives. Conclusion Striatal GM volume, global brain atrophy and PVS burden may serve as differential indicators of disease manifestation in HD. The Raven's Standard Progressive Matrices could be a cognitive test worth to consider in the differentiation of vulnerability versus overt disease in HD.

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INECO Frontal Screening (IFS): A brief, sensitive, and specific tool to assess executive functions in dementia – ERRATUM

Cited by 46 publications

References 41 publications

The Spanish version of the Addenbrooke's Cognitive Examination — Revised (ACE-R) in subcortical ischemic vascular dementia

The Spanish version of the Addenbrooke's Cognitive Examination — Revised (ACE-R) in subcortical ischemic vascular dementia

Utility of the INECO frontal screening (IFS) in the detection of executive dysfunction in patients with relapsing-remitting multiple sclerosis (RRMS)

Structural neuroimaging differentiates vulnerability from disease manifestation in colombian families with Huntington's disease

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