It is desired to increase breastfeeding rates at national and international level. However, maternal smoking during the lactation period, which has negative effects on breastfeeding, is common both in our country and in Europe. Smoking during the breastfeeding period of the mother is directly related to the inhibition of the milk let-down reflex and the decrease in milk production. Maternal smoking during lactation causes changes in infants' sleep/wake patterns, deterioration of the pro-oxidant-antioxidant balance of breast milk, and low iodine-based breast milk transfer. In addition, in the babies of smoker mothers; bad taste from breast milk, restlessness, possibility of getting respiratory system infections such as pneumonia, asthma, bronchitis, risk of sudden infant death syndrome tendency to colic and obesity are more higher. Some mothers who smoke believe that it is safer to give formula than to breastfeed. In addition, there are mothers who ask questions such as whether smoking spoils the quality and taste of my milk, what can I do to make smoking less harmful to my baby, I smoke, can I breastfeed my baby in clinical practice. Medical staff Ali should be aware of the effects of nicotine exposure on infants of breastfeeding and smoking mothers during breastfeeding education and counseling, and should pay enough attention to this issue. Healthcare professionals should seize every opportunity to increase interest in breastfeeding, to raise awareness of the harm caused by cigarette exposure in the newborn, and to encourage smoking cessation.For this reason, the aim of this review is to review the literature on breastfeeding and smoking.