This was an open label, non-randomized and non-comparative study to assess effect of Colicarmin plus drops on Colic, Griping Pain, Indigestion, Flatulence, and diarrhea in Paediatrics patients. A total 75 patients were enrolled in study, all the patients were followed-up at the end of treatment and clinical examination was done, along with recording of adverse events. Infants below 6 months: 1-4 drops, 4-6 times a day, 6 months to 1 year: 4-5 drops, 4-6 times a day, 1 year to 3 years: 5-6 drops, 4-6 times a day, 3 years to 5 years: 6-10 drops, 4-6 times a day. Colic and griping pain: More than 50% patients got relief in five minutes, Indigestion: More than 50% patients were cured in 24 hours, Flatulence: More than 50% got relief in just 15 minutes, Diarrhea during teeth eruption: More than 50% patients got relief in 4 days. Colicarmin plus drops an Ayurvedic formulation has benefits like digestive, carminative and spamolytic which gives relief from colic and griping pain, indigestion, flatulence, nausea and diarrhea without any side effects.