Infantile myofibroma: a firm, round plaque in an infant

Abstract

Case presentationInfantile myofibroma: a firm, round plaque in an infant.

An Infant With a Congenital Violaceous Plaque: Answer

“…Infantile myofibromatosis (IM) is a rare benign fibromatous spindle cell tumor; of which, there are 3 subtypes: solitary, multicentric, and multicentric with visceral involvement. 1–4 Solitary IM, seen in our case, is the most common IM subtype (>50% of cases). 1–4 Clinically, solitary IM specifically consists of firm flesh-colored to purple nodules of 0.5–7.0 cm in diameter, in the skin and subcutaneous tissue.…”

“…1–4 Solitary IM, seen in our case, is the most common IM subtype (>50% of cases). 1–4 Clinically, solitary IM specifically consists of firm flesh-colored to purple nodules of 0.5–7.0 cm in diameter, in the skin and subcutaneous tissue. 3 The head and neck are the most common sites for IM to appear, followed by the extremities and trunk.…”

Myofibroma of infancy and its mimickers

“…MOI may present as a nodule, papillomatous, or atrophic lesion that can be deep, superficial, mobile, or fixed. 2,3 In our patient, the lesion was an infiltrated purple-red plaque with erosion on the surface. The localization is usually the head, neck, or trunk, whereas in our case, it was a foot.…”

“…Myofibroma of infancy (MOI) is a rare benign tumor of mesenchymal origin, which is, at the same time, the most common fibromatous tumor in childhood. 1,2 It occurs more frequently in (d) hemangioma, (e) rapidly involuting congenital hemangioma, (f) verrucous hemangioma, (g) cutis marmorata telangiectatica congenita, (h) congenital fibrosarcoma, (i) Kaposiform hemangioendothelioma, (j) complication after venous catheter implantation, (k) pressure ulcers. males, unlike our patient, and about 50% of cases are already present at birth.…”

“…males, unlike our patient, and about 50% of cases are already present at birth. 2 It has occasionally been reported in adults. 3 Its various clinical presentations pose diagnostic challenges, which may delay the proper management.…”