“…However, none achieved remission via macrolide monotherapy; instead, macrolides were used in conjunction with topical corticosteroids, systemic corticosteroids, nicotinamide, and ranitidine [2 5]. In two patients, macrolides and topical/systemic corticosteroid combination therapy were used as initial treatment [2,5], whereas two others were given macrolides as corticosteroid-sparing agents following failure to control BP using initial corticosteroid therapy or corticosteroid with antibiotic combination therapy [3,4].…”