Infantile tremor syndrome

Garg, B. K.; Srivastava, J. N.

doi:10.1007/bf02756643

Cited by 23 publications

(22 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the present study, the age of presentation was 6–18 months with mean, SD of 11, 3.1 months which was similar to that reported in other studies. [ 7 8 9 ] Number of males were more than females, as was seen in earlier studies. [ 8 10 11 ] We observed that cases were present throughout the year, with two peaks in the months of May and November which is similar to Ghai,[ 1 ] Sharda and Bhandari,[ 12 ] but contrary to Charles et al .,[ 8 ] Sirolia and Arya[ 7 ] Majority of patients were from a rural background and lower middle socioeconomic status, as was observed by Bajpai et al .…”

Section: Discussionsupporting

confidence: 69%

Infantile tremor syndrome in modern times

et al. 2017

View full text Add to dashboard Cite

Background:Infantile tremor syndrome (ITS) is a clinical syndrome of acute or gradual onset of mental and psychomotor changes, pigmentary disturbances of hair and skin, pallor, and tremors in malnourished children aged between 5 months and 3 years. It is a well-known entity, but the exact etiopathogenesis is still not known.Setting and Design:Prospective observational study carried out in the Department of Pediatrics at Dr RPGMC Tanda, Kangra in Himachal Pradesh.Materials and Methods:Demographic, clinical, and laboratory profile of 25 children with the diagnosis of preinfantile and ITS was collected who were admitted from May 2014 to June 2015.Statistical Analysis:Descriptive analysis was performed using SPSS 17 trial version.Results:These children accounted for 0.5% of total pediatric admissions. Median, standard deviation age was 10, 3.1 months. Male to female ratio was 1.27:1. Cases were present throughout the year with two peaks observed in the months of May and November. This disease was found to be more common in higher birth order (68%). Complementary feeding, that too improper, was initiated in only 4 cases (16%). Ninety-six percent cases presented with comorbid illnesses. Respiratory tract infection was the most common association, followed by urinary tract infection. There was moderate anemia with dimorphic picture (40%). Thirteen (52%) had vitamin B12 levels below normal. Magnesium levels, though statistically insignificant (P = 0.8) were lower in patients with tremors.Conclusion:This is a disease of multi-micronutrient deficiency, which can be present either alone or in association. Educating women about proper nutrition during pregnancy and timely administration of complementary feeding is of utmost importance.

show abstract

Section: Discussionsupporting

confidence: 69%

Infantile tremor syndrome in modern times

et al. 2017

View full text Add to dashboard Cite

show abstract

“…15,16 In our study 6 -12 mo age group was significantly associated with ITS which is similar to previous studies but Sachdev et al reported that 13-18 mo was most affected group. 4,9,10,12,13,17,18 Mean age of our study population was 13.72 mo which is similar to study by Udani et al (13.9mo). Like previous studies there was slight preponderance of ITS in boys in our study also though the difference is not statistically significant.…”

Section: Discussionsupporting

confidence: 86%

“…Bajpai et al, Sachdev et al and Garg et al also reported that all children in their study were from lower socioeconomic status. 10,12,13 Similarly Ramkumar et al and Arya et al also found that majority of their patients with ITS were from lower socioeconomic status. 9,14 Mothers of significant number of these patients were illiterate and housewives whereas fathers were either illiterate or literate up to primary standard and unskilled laborers.…”

Section: Discussionmentioning

confidence: 90%

“…Most of studies reported regression of milestones (6.5%-100%) although delayed milestone (30.4%-80.3%) were also reported in some studies. 3,4,9,10,[12][13][14][18][19][20] Most of the workers have found vitamin B 12 deficiency in children with ITS but to the best of our knowledge and thorough web search ours is the first planned study to assess iron (serum ferritin) and folate status along with vitamin B 12 in children with ITS. 3,4,21 In our study all the ITS patients were anemic but none of them had low levels of folate or ferritin which are commonly responsible for anemia in children.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Assessment of iron, folate and vitamin B12 status in children with infantile tremor syndrome

Rajpoot

Poswal

Goyal

2016

Int J Contemp Pediatr

View full text Add to dashboard Cite

“…Sachdev et al 1 , Bajpai et al 2 , Garg and Srivastava. 3 , Mathur et al 4 , Deshpande and Ingle. 5 Agarwal and Katiyar.…”

Section: Resultsmentioning

confidence: 99%

Study of Clinico- Epidemiological Profile of Patients Admitted With Infantile Tremor Syndrome (Its) and Status of Trace Elements (Zinc, Copper) Deficiency in Them

Makwana¹,

Garg²,

Mourya³

et al. 2017

jebmh

View full text Add to dashboard Cite

BACKGROUND Under nutrition is one of the major problems in the field of Paediatrics. The greatest risk of malnutrition is in the first two years of life. The effects of this early damage on health, brain development, intelligence, educability and productivity are potentially reversible. The current study was an attempt to find out the clinico epidemiological profile, evaluate them for trace elements deficiency and most appropriate management options in those who are admitted with infantile tremor syndrome. MATERIALS AND METHODS The current study was a hospital based cross sectional study that was conducted in the Department of Paediatrics, Dr. S. N. Medical College Jodhpur. Duration of study was One Year. Any child up to the age of three years of age admitted in the paediatric wards with typical features of infantile tremor syndrome. RESULTS Maximum numbers of patients were found between 6 months to 12 months of age, there was slight male predominance. The majority of infants in our study (85%) were exclusively breast fed, 66% of cases were having low serum Copper level. 9% of cases were having low serum zinc level. 8% of cases were having low serum copper level with tremors. CONCLUSION In our study the fact that NTS is mainly seen in children who are exclusively breast feed for a longer period with delayed introduction of weaning foods. The main presenting features remain developmental delay, hyper pigmentation and anemia. Among nutritional factors, deficiency of copper and zinc in children plays a big role in development of disease. Thus to prevent the development of nutritional tremor syndrome stress should be on early timely introduction of weaning foods, especially rich in copper and zinc. What is already known about this Study-low levels of trace elements like copper and zinc may be responsible for typical clinical manifestations in patients of infantile tremor syndrome. Pronged and Exclusive breast feeding further aggravate these features. What this Study Adds-Pronged and Exclusive breast feeding along with low levels of trace elements like copper and zinc are responsible for typical clinical manifestations in patients of infantile tremor syndrome.

show abstract

Infantile tremor syndrome

Cited by 23 publications

References 6 publications

Infantile tremor syndrome in modern times

Infantile tremor syndrome in modern times

Assessment of iron, folate and vitamin B12 status in children with infantile tremor syndrome

Study of Clinico- Epidemiological Profile of Patients Admitted With Infantile Tremor Syndrome (Its) and Status of Trace Elements (Zinc, Copper) Deficiency in Them

Contact Info

Product

Resources

About