Infantile tumoral calcinosis of the cervical spine presenting as torticollis

Ashraf, Ali; Diehn, Felix E.; Luetmer, Patrick H.; Lane, John I.; Fritchie, Karen; Larson, A. Noelle

doi:10.1016/j.clinimag.2015.09.007

Cited by 3 publications

(4 citation statements)

References 11 publications

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“… 6 Lesions are often cystic or multiloculated, which may manifest as a “sedimentation sign” on imaging due to fluid-fluid levels from calcium layering. 14 , 20 , 23 Earlier lesions may contain a large amount of eosinophilic material, but as they continue to calcify over time, the crystals can condense and the overall appearance may become more basophilic, with some cases containing psammomatous elements.…”

Section: Discussionmentioning

confidence: 99%

“…Nonoperative modalities of management have included observation, due to reported cases of spontaneous resolution, 23 or addressing an underlying medical condition promoting soft tissue calcification. 3 , 4 Nevertheless, surgery is frequently indicated for spinal tumoral calcinosis due to progressive neurological symptoms.…”

Section: Discussionmentioning

confidence: 99%

“…[3][4][5] Tumoral calcinosis can arise in patients with underlying genetic or metabolic disorders that result in hyperphosphatemia, 19 uremia, 3,4,20 scleroderma, 5,13,18,21 rheumatoid arthritis, 22 and seronegative spondyloarthropathy. 12 Idiopathic cases have been reported [9][10][11]16,23,24 as well as those arising secondary to surgery or trauma at the site of involvement. 14,25 In the spine, posited mechanisms of calcium phosphate crystal deposition in the spine include origination from the articular capsule, disc or facet joint degeneration, and hemorrhage with foamy histiocytic aggregation.…”

Section: Observationsmentioning

confidence: 99%

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Navigation-assisted resection of tumoral calcinosis of the lumbosacral spine: illustrative case

Tang¹,

Sullivan²,

Tubre

et al. 2022

Journal of Neurosurgery: Case Lessons

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BACKGROUND Tumoral calcinosis is an uncommon disease resulting from dystrophic calcium phosphate crystal deposition, with only 7% of cases involving the spine, and it may diagnostically mimic neoplasms. OBSERVATIONS In this case, a 54-year-old woman with history of systemic scleroderma presented with 10 months of progressive left lumbosacral pain. Imaging revealed an expansile, 4 × 7-cm, well-circumscribed mass in the lumbosacral spine with L5–S1 neuroforaminal compression. Because intractable pain and computed tomography (CT)-guided needle biopsy did not entirely rule out malignancy, operative management was pursued. The patient underwent L4–S2 laminectomies, left L5–S1 facetectomy, L5 and S1 pediculectomies, and en bloc resection, performed under stereotactic CT-guided intraoperative navigation. Subsequently, instrumented fusion was performed with L4 and L5 pedicle screws and S2 alar-iliac screws. Pathological examination was consistent with tumoral calcinosis, with multiple nodules of amorphous basophilic granular calcified material lined by histiocytes. There was no evidence of recurrence or neurological deficits at 5-month follow-up. LESSONS Because spinal tumoral calcinosis may mimic neoplasms on imaging or gross intraoperative appearance, awareness of this clinical entity is essential for any spine surgeon. A review of all case reports of lumbosacral tumoral calcinosis (n = 14 from 1952 to 2016) was additionally performed. The case featured in this report presents the first known case of navigation-assisted resection of lumbosacral tumoral calcinosis.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Observationsmentioning

confidence: 99%

See 1 more Smart Citation

Navigation-assisted resection of tumoral calcinosis of the lumbosacral spine: illustrative case

Tang¹,

Sullivan²,

Tubre

et al. 2022

Journal of Neurosurgery: Case Lessons

View full text Add to dashboard Cite

show abstract

“…Le traitement est chirurgical mais les lésions peuvent récidiver [1]. Cette affection peut être héréditaire, consécutive à une maladie chronique comme l'insuffisance rénale ou survenir de manière sporadique, auquel cas elle est fréquemment attribuée à des traumatismes répétés mineurs [2].…”

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