Infants undergoing antenatal genetic diagnosis: A preliminary report

Allen, Haddijatou; Sergovich, F. R.; Stuart, E.M.; Pozsonyi, J; Murray, Brenda-Lee

doi:10.1016/s0002-9378(16)33784-x

Cited by 16 publications

(2 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The failure rate of amniotic fluid cell culture in the present study is 1%; others reported either similar data (Nadler and Gerbie, 1970) or higher figures: 10% (Milunsky and Atkins, 1974;Allen et al, 1974) and 300o (Robinson et al, 1973).…”

Section: Discussionsupporting

confidence: 51%

Prenatal diagnosis of genetic disorders.

Niermeijer¹,

Sachs²,

Jahodova³

et al. 1976

Journal of Medical Genetics

View full text Add to dashboard Cite

Summary. Three hundred and fifty pregnancies were monitored by transabdominal amniocentesis in the fourteenth to sixteenth week of gestation followed by karyotyping or The safety and reliability of amniocentesis and the possible effects on the outcome of pregnancy are evaluated. Prenatal diagnosis offers a promising alternative for parents who are at risk of having a child with a genetic disease which can be detected in amniotic fluid or in cultured amniotic fluid cells.Since the first reports of fetal karyotyping (Steele and Breg, 1966;Jacobson and Barter, 1967) and biochemical assays (Nadler, 1968(Nadler, , 1969 after amiocentesis in early pregnancy, increasing numbers of centres have gained experience on prenatal diagnosis of genetic diseases. Recent reviews (Milunsky, 1973;Hsu and Hirschhorn, 1974) show how the application of prenatal diagnosis in genetic counselling has already enabled many parents at risk for genetic disease to have non-affected children.

show abstract

Section: Discussionsupporting

confidence: 51%

Prenatal diagnosis of genetic disorders.

Niermeijer¹,

Sachs²,

Jahodova³

et al. 1976

Journal of Medical Genetics

View full text Add to dashboard Cite

show abstract

“…Non-lethal injuries to the fetus, although occurring more often in third than in second trimester amniocentesis, have been observed in the latter as gangrene of a fetal limb by supraclavicular needle puncture (Lamb, 1975) as ocular trauma (Merin and Beyth, 1980), as disruption of a patellar tendon (Epley et al, 1979), as cardiac puncture (Manganiello et al, 1979) or as arterio-venous fistula (Gottdiener et al, 1975;Fellows and Griscom, 1976). Occasional dermal scarring in newborn infants may also be attributed to skin puncture (Allen et a,, 1974;Golbus et al, 1974;Broome et al, 1976;Karp and Hayden, 1977;Rauskolb el al, 1978;Epley et al, 1979;Gillberg et al, 1979).…”

mentioning

confidence: 99%

Intestinal Atresia Caused by Second Trimester Amniocentesis

Therkelsen

Rehder

1981

BJOG

View full text Add to dashboard Cite

show abstract

Needle puncture scars from midtrimester amniocentesis

Raimer¹

1984

Archives of Dermatology

View full text Add to dashboard Cite

A neonate was noted to have two depressed scars on the upper part of the back at birth that we believe resulted from midtrimester amniocentesis; no underlying injury was apparent. Scar formation from needle puncture occurs in an estimated 1% to 3% of the infants whose mothers have undergone midtrimester diagnostic amniocentesis. The scars most commonly are depressed, dimplelike, and measure 1 to 2 mm in diameter, although linear scarring may also occur. Single or multiple scars may be present, and, in seven of the 36 infants previously described in the literature, internal injuries also occurred as a result of the needle puncture.

show abstract

Infants undergoing antenatal genetic diagnosis: A preliminary report

Cited by 16 publications

References 4 publications

Prenatal diagnosis of genetic disorders.

Prenatal diagnosis of genetic disorders.

Intestinal Atresia Caused by Second Trimester Amniocentesis

Needle puncture scars from midtrimester amniocentesis

Contact Info

Product

Resources

About