Infarto agudo de miocardio secundario a granulomatosis de Wegener

García-Iglesias, Francisca; García-Tobaruela, Almudena; Uriol, P Lavilla; Aguado, A. Gil; Beneitez, Javier Fuertes; Vinuesa, Pastora Gallego García de; Gómez-Guindal, José Antonio; Daza, José A. Sobrino; Martín-Jadraque, Luís

doi:10.1016/s0300-8932(98)74753-0

Cited by 9 publications

(1 citation statement)

References 8 publications

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“…For example, acute coronary syndrome and left anterior descending artery occlusion similar to our case were detected in a young male patient with Wegener's granulomatosis. (10) In another example, in two different patient groups with Takayasu artery and rheumatoid arthritis, early atherosclerosis was observed in those with Takayasu arteritis. (11) This was thought to be because atherosclerosis was associated with chronic systemic inflammation without cardiovascular risk factors.…”

Section: Discussionmentioning

confidence: 97%

A Case of Acute Coronary Syndrome Under Immunsupression Who Is the Criminal Neutrophils or T Cells?

OKTAY

Sertdemi̇r

İçli̇

2023

Journal of Emergency Medicine Case Reports

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Chronic granulomatous disease (CGD) is a primary immunodeficiency characterized by recurrent, life-threatening bacterial and fungal infections of the skin, airways, lymph nodes, liver, brain, and bones. These infections most commonly occur in organs in contact with the outside world (lungs, gastrointestinal tract, and skin), as well as in lymph nodes that drain these structures. While involvement can be seen in many organs, there is no known cardiovascular involvement. Our case is an ACS case that has a different place in the literature because acute coronary syndrome (ACS) was seen in a 20-year-old male patient with a diagnosis of chronic granulomatous disease.

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Section: Discussionmentioning

confidence: 97%

A Case of Acute Coronary Syndrome Under Immunsupression Who Is the Criminal Neutrophils or T Cells?

OKTAY

Sertdemi̇r

İçli̇

2023

Journal of Emergency Medicine Case Reports

View full text Add to dashboard Cite

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Direct percutaneous coronary intervention for NSTEMI in a patient with seropositive Wegener’s granulomatosis

2005

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A case of a 49-year-old man who presented with symptoms of generalized classical Wegener's granulomatosis with the exceptional complication of acute non-ST-elevation myocardial infarction (NSTEMI) is reported. Coronary arteriography revealed an extensive arteritis with multi-local stenosis of the left anterior descending coronary artery. The culprit lesion was treated by stent implantation with success while immunosuppressive treatment with cyclophosphamide and prednisolone was continued. Using arteriography, 4 months later we found normal coronary arteries without manifestation of vasculitis. Within 8 months of medical treatment complete remission was achieved and therapy was changed to low-dose methotrexate once a week. Meanwhile medical treatment has been stopped entirely. The patient is in good clinical condition. This case indicates that the adverse event of coronary vasculitis in any patient suffering from primary or secondary vasculitis can occur. Clinically significant myocardial ischemia can occur and can even lead to myocardial infarction.

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