Infección congénita por citomegalovirus en hijos de madres infectadas por el VIH

Gabriel, Miguel Ángel Marín; Ibieta, M Fernández; Tomé, María Isabel González; Lozano, J. Saavedra; Sánchez, V Barajas; Conejo, Pablo Rojo

doi:10.1157/13070179

Cited by 17 publications

(12 citation statements)

References 12 publications

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“…11, 13–16, 26–30 Among HIV-infected infants, cCMV rates correlated with those reported in other studies, which typically ranged from 4.3% to 21%; 11, 12, 14, 16, 29 but included some studies with rates as low as 0% 13 and others with rates as high as 26–29%. 31, 32…”

Section: Discussionmentioning

confidence: 99%

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Congenital Cytomegalovirus and HIV Perinatal Transmission

Adachi

Ank

et al. 2018

Pediatric Infectious Disease Journal

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Section: Discussionmentioning

confidence: 99%

“…Some studies have suggested that the use of HAART by pregnant HIV-infected women may reduce cCMV rates among their HIV-exposed infants by improving their immune status during pregnancy. 11, 26–28, 31…”

Section: Discussionmentioning

confidence: 99%

Congenital Cytomegalovirus and HIV Perinatal Transmission

Adachi

Ank

et al. 2018

Pediatric Infectious Disease Journal

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“…Published rates of congenital CMV infection in HIV-infected infants have varied widely, from 0% 13 to as high as 26%, 8 the two largest studies showing 10% transmission. 11, 25 Several groups have described high rates of congenital CMV infection in babies with specifically in utero HIV infection: 4/14 (29%) in Kenyan infants and 6/49 (12%) in a French cohort.…”

Section: Discussionmentioning

confidence: 99%

The Interrelated Transmission of HIV-1 and Cytomegalovirus During Gestation and Delivery in the Offspring of HIV-Infected Mothers

Khamduang

Jourdain

Sirirungsi

et al. 2011

JAIDS Journal of Acquired Immune Deficiency Syndromes

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Our objective was to analyze, in formula-fed infants, correlates of HIV mother-to-child transmission, including cytomegalovirus (CMV) infection. HIV-infected infants were matched with HIV-uninfected by maternal HIV RNA in a case-control design. Infant CMV infection was determined by CMV-IgG at 18 months and timed by earlier CMV-IgM or -DNA. Correlations were assessed using logistic regression. In utero HIV infection was independently associated with congenital CMV infection (P=0.01), intrapartum HIV infection with congenital-plus-intrapartum/neonatal CMV infection (P=0.01), and overall HIV with overall CMV infection (P=0.001), as well as prematurity (P=0.004). Congenital and acquired CMV infections are strong independent correlates of mother-to-child HIV transmission.

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“…Globally, CMV is the most commonly transmitted infection from mother to child, occurring in 0.2 percent–2.2 percent of live-born infants in the United States with similar transmission rates likely in resource limited settings. The prevalence of CMV infection among HIV-infected pregnant women is higher than in the general population, with approximately 90% of HIV-infected pregnant women co-infected with CMV [13]. …”

Section: Long-term Impact Of Hiv Exposure On Infant and Childhoodmentioning

confidence: 99%

HIV-exposed infants

Sugandhi

Rodrigues

Kim

et al. 2013

Aids

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Summary Each year over a million infants are born to HIV infected mothers though with scale up of prevention of mother to child transmission (PMTCT) interventions, only 210,000 of the 1.3 million infants born to mothers with HIV/AIDS in 2012 became infected. Current programmatic efforts directed at infants born to HIV-infected mothers are primarily focused on decreasing their risk of infection, but this emphasis on maternal interventions has meant follow-up of exposed infants has been poor. Programs are struggling to retain this population in care until the end of exposure, typically at the cessation of breastfeeding, between 12 and 24 months of age. But HIV exposure is a life-long condition that continues to impact the health and well-being of a child long after exposure has ended. A better understanding of the impact of HIV on exposed infants is needed and new programs and interventions must take into consideration the long-term health needs of this growing population. The introduction of lifelong treatment for all HIV-infected pregnant women is an opportunity to rethink how we provide services adapted for the long-term retention of mother-infant pairs.

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Infección congénita por citomegalovirus en hijos de madres infectadas por el VIH

Cited by 17 publications

References 12 publications

Congenital Cytomegalovirus and HIV Perinatal Transmission

Congenital Cytomegalovirus and HIV Perinatal Transmission

The Interrelated Transmission of HIV-1 and Cytomegalovirus During Gestation and Delivery in the Offspring of HIV-Infected Mothers

HIV-exposed infants

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