Infected total knee arthroplasty

Bindelglass, David F.

doi:10.1097/00001433-199702000-00006

Cited by 4 publications

(7 citation statements)

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“…It included a 6-8 hour fast, analysis of serum glucose levels and avoiding physical exercise previously. The radiotracer used was 18 FDG, the isotope of which is a positron emitter ( 18 F -), and which was obtained in a cyclotron model Cyclone 18-9-IBA. 6.2 MBq/kg was administered endovenously in the forearm.…”

Section: Positron Emission Tomography Equipmentmentioning

confidence: 99%

“…A minimum of 40 minutes elapsed after injection of the 18 FDG, since it is advisable to wait up to 50-60 minutes to reach a maximum stable glucose incorporation rate. Oral and/or intravenous hydration of the patient was carried out after injection of the 18 FDG, carrying out bladder catheterization (Foley catheter) and the administration of furosemide (0.25 mg/kg).…”

Section: Positron Emission Tomography Equipmentmentioning

confidence: 99%

“…Oral and/or intravenous hydration of the patient was carried out after injection of the 18 FDG, carrying out bladder catheterization (Foley catheter) and the administration of furosemide (0.25 mg/kg). In addition, in some cases, the bladder was filled retrogressively with physiological serum to remove possible artefacts caused by the activity of the 18 FDG filtered in the concentrated urine over the course, serving also as an anatomical reference.…”

Section: Positron Emission Tomography Equipmentmentioning

confidence: 99%

“…The estimated cost of each treatment of an infected arthroplasty in 1995 was between 50-60 thousand dollars, which in the U.S. means a national expenditure of between 200 and 250 million dollars annually. 18 The estimated expenditure in the United Kingdom, with approximately 50,000 THP annually and around 500 cases of infection in 1990, is £16 million per year. 8 The differential diagnosis between septic and aseptic loosening is therefore fundamental, both for choosing the correct treatment and for assessing its evolution and, sometimes, the diagnosis of safety is not reached until removal and study of the prosthetic material.…”

Section: Introductionmentioning

confidence: 99%

“…[40][41][42][43][44][45] The objective of this study is to be able to establish an effective and efficient diagnostic protocol for prosthetic mobilisation through the prospective evaluation of clinical, microbiological, imaging (including 18 FDG-PET) and histopathological findings and the relationship between them.…”

Section: Introductionmentioning

confidence: 99%

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18FDG-PET: a new diagnostic approach in hip prosthesis infection

García-Barrecheguren¹,

Fraile²,

Santana³

et al. 2007

Revista Española de Medicina Nuclear (English Edition)

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Infection following hip arthroplasties can present a diagnostic challenge. No test is 100 % sensitive and 100% specific; this prospective study was undertaken to evaluate the utility of FDG-PET imaging for diagnosing infected joint replacements. 24 hip joint replacements were studied prospectively and we have complete diagnoses with clinical signs and symptoms, laboratory tests, radiography, joint aspiration, radionuclide imaging including FDG-PET, and histopathologic examination. 11 of 24 prostheses were infected. The sensitivity and specificity of PET for detecting infection associated with prostheses were 64.3% and 64.7% respectively, in our study. FDG imaging is not useful in patients with suspected prosthetic infection as a screening test.

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Section: Positron Emission Tomography Equipmentmentioning

confidence: 99%

Section: Positron Emission Tomography Equipmentmentioning

confidence: 99%

Section: Positron Emission Tomography Equipmentmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

18FDG-PET: a new diagnostic approach in hip prosthesis infection

García-Barrecheguren¹,

Fraile²,

Santana³

et al. 2007

Revista Española de Medicina Nuclear (English Edition)

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Advances in the diagnosis of infection in prosthetic joint implants

Mariani

Tuan

1998

Molecular Medicine Today

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Molecular Detection of Infection in Total Knee Arthroplasty: A Clinical Correlation

Mariani

Booth

Levine

et al. 1999

J. Musculoskelet. Res.

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Total knee arthroplasty patients displaying symptoms consistent with either implant biomechanical failure or periprosthetic infection, and requiring revision surgery, had synovial fluid aspirated from the affected joint and subjected to standard microbiological culture testing for bacterial infection. In this study, an aliquot of each synovial fluid specimen was analyzed for infection using the rapid, sensitive molecular assay of polymerase chain reaction (PCR), designed to selectively amplify bacterial deoxyribonucleic acid. Decisions concerning surgical procedures performed during revision surgery were based entirely on clinical criteria, including standard preoperative evaluation for infection, independent of PCR results. In total, on the basis of pre- and/or intraoperative clinical data in conjunction with postoperative information, septic failure was determined in 31 of 50 patients, all of whom tested positive using the PCR assay. This correlative study validates the application of the PCR assay for clinical evaluation of arthroplasty infections.

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Infected total knee arthroplasty

Cited by 4 publications

References 0 publications

18FDG-PET: a new diagnostic approach in hip prosthesis infection

18FDG-PET: a new diagnostic approach in hip prosthesis infection

Advances in the diagnosis of infection in prosthetic joint implants

Molecular Detection of Infection in Total Knee Arthroplasty: A Clinical Correlation

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