Infection

Agarwal, Prerana; Romano, Luigia; Prosch, Helmut; Schueller, Gerd

doi:10.1007/174_2016_38

Cited by 1 publication

(1 citation statement)

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“… 35 Interstitial inflammatory infiltrates and oedema are detected on imaging as ground glass opacities. 35 , 36 Therefore, the differential perfusion of the lung lobes may result in greater disease manifestation in those areas which are better perfused. 21 In addition, differential lymphatic drainage may result in the differential clearing of inflammatory mediators and cellular debris, contributing further to the differential lobar manifestations.…”

Section: Discussionmentioning

confidence: 99%

A study of the chest imaging findings of adult patients with COVID-19 on admission to a tertiary hospital in Johannesburg, South Africa

Ord

Zamparini

Lorentz

et al. 2022

Southern African Journal of Infectious Diseases

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Background: South Africa has experienced multiple waves of the coronavirus disease 2019 (COVID-19) with little research documenting chest imaging features in an human immunodeficiency virus (HIV) and tuberculosis (TB) endemic region.Objectives: Describe the chest imaging features, demographics and clinical characteristics of COVID-19 in an urban population.Method: Retrospective, cross-sectional, review of chest radiographs and computed tomographies (CTs) of adults admitted to a tertiary hospital with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, between 01 May 2020 and 30 June 2020. Imaging was reviewed by three radiologists. Clinical parameters and laboratory data were analysed.Results: A total of 113 adult patients with a mean age of 46 years and 10 months were included. A total of 113 chest radiographs and six CTs were read. Nineteen patients were HIV-positive (16.8%), 40 were hypertensive and diabetic (35.4%), respectively, and one had TB (0.9%). Common symptoms included cough (n = 69; 61.6%), dyspnoea (n = 60; 53.1%) and fever (n = 46; 40.7%). Lower zone predominant ground glass opacities (58.4%) and consolidation (29.2%) were most frequent on chest radiographs. The right lower lobe was most involved (46.9% ground glass opacities and 17.7% consolidation), with relative sparing of the left upper lobe. Bilateral ground glass opacities (66.7%) were most common on CT. Among the HIV-positive, ground glass opacities and consolidation were less common than in HIV-negative or unknown patients (p = 0.037 and p = 0.05, respectively).Conclusion: COVID-19 in South Africa has similar chest imaging findings to those documented globally, with some differences between HIV-positive and HIV-negative or unknown patients. The authors corroborate relative sparing of the left upper lobe; however, further research is required to validate this currently unique local finding.

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