Infection à Geotrichum capitatum chez un patient neutropénique. À propos d'un cas et revue de la littérature

Fouassier, Marc; Joly, D; Cambon, M.; Peigue-Lafeuille, H.; P, Condat

doi:10.1016/s0248-8663(98)80868-0

Cited by 21 publications

(17 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Les géotrichoses sont des infections opportunistes qui se développent quand il existe un terrain favorable, particulièrement une immunodépression ou une destruction de la flore microbienne normale, ainsi que l'utilisation d'antibiotique à large spectre [5,7,9,12]. On retrouve la neutropénie profonde comme facteur de risque important souvent objectivé chez les patients atteints de géotrichose, cette neutropénie secondaire à une leucémie aiguë ou une greffe de la moelle osseuse ainsi que les patients sous chimiothérapie anticancéreuse [9,12].…”

Section: Discussionunclassified

See 1 more Smart Citation

Infection pulmonaire à Geotrichum capitatum à propos d’un cas et revue de la littérature

El-Hassani

Deham

Touaoussa

et al. 2014

Journal de Mycologie Médicale

View full text Add to dashboard Cite

Section: Discussionunclassified

“…Ces deux types d'infections sont les plus couramment rapportées en littérature [5][6][7]9,12]. Les formes pulmonaires isolées semblent rares [9].…”

Section: Discussionunclassified

Infection pulmonaire à Geotrichum capitatum à propos d’un cas et revue de la littérature

El-Hassani

Deham

Touaoussa

et al. 2014

Journal de Mycologie Médicale

View full text Add to dashboard Cite

“…Recent epidemiologic trends indicate a shift toward previously uncommon opportunistic fungi, such as Trichosporon infection, in patients receiving cytotoxic drugs (28 -31). Geotrichum capitatum is a potentially invasive fungal infection in these patients, leading to death in 50 -70% of cases (28,31); the portal of entry of G. capitatum is digestive or respiratory (20,28 -31). We report, to our knowledge, the first case of digestive G. capitatum infection complicated with septicemia in a DM patient.…”

Section: Marie Et Almentioning

confidence: 99%

Opportunistic infections in polymyositis and dermatomyositis

Marie¹,

Hachulla²,

Chérìn³

et al. 2005

Arthritis & Rheumatism

166

126

View full text Add to dashboard Cite

Objective. To assess prevalence and characteristics of opportunistic infections in patients with polymyositis/dermatomyositis (PM/DM). To determine the predictive values for opportunistic infections on clinical presentation, biochemical findings, and paraclinical features of PM/DM to detect patients at risk of opportunistic infections. Methods. The medical records of 156 consecutive PM/DM patients in 3 medical centers were reviewed. Results. Eighteen PM/DM patients (11.5%) developed opportunistic infections. The majority of patients exhibited an opportunistic infection after the onset of PM/DM (89% of cases). Opportunistic infections occurred most frequently during the first year following PM/DM diagnosis (62.5%). The pathogen microorganisms responsible for opportunistic infections were various, i.e., Candida albicans, Pneumocystis carinii, Aspergillus fumigatus, Geotrichum capitatum, Mycobacterium avium-intracellulare complex, M. xenopi, M. marinum, M. tuberculosis, Helicobacter heilmanii, cytomegalovirus, and herpes simplex virus. Mortality rates were as high as 27.7% in these PM/DM patients. Higher mean daily doses of steroids, lymphopenia, and lower serum total protein levels were significantly more frequent in the group of PM/DM patients with opportunistic infections. Conclusion. Our study underscores the high frequency of opportunistic infections in PM/DM, resulting in an increased mortality rate. It also indicates that a great variety of microorganisms are responsible for opportunistic infections, although they were more often due to fungi (>50% of cases). Our series highlights a predominance of both lung and digestive opportunistic infections (89% of cases). In addition, our results suggest that PM/DM patients presenting with factors predictive of opportunistic infection may require closer monitoring.

show abstract

“…The severity of neutropenia is also significant: 94% of patients have neutrophil counts less than 100/mm 3 [5]. Other noted risk factors include: recent broad-spectrum antibiotics [3,6], cytotoxic chemotherapy [5], corticosteroids [4], and preparation for hematopoietic stem cell transplantation [3].…”

Section: Discussionmentioning

confidence: 99%

“…Bc may infect the lungs, endocardium, kidneys, liver and, exceptionally, bones and the central nervous system. Pneumonia with septicaemia carries the worst prognosis [6]: death is the outcome in 57% of cases [5]. In contrast, spondylodiscitis normally resolves completely with treatment [1,2,7].…”

Section: Discussionmentioning

confidence: 99%

Cervical Spondylodiscitis Caused by Blastoschizomyces capitatus

et al. 2008

View full text Add to dashboard Cite

A 37-year-old woman, during her second remission of acute myeloid leukemia, presented with severe neck pain and cervico-brachial neuralgia. Investigation revealed a C5-C6 spondylodiscitis. A CT-guided anterior biopsy decompressed the mass, immediately alleviated the symptoms, and isolated a rare yeast: Blastoschizomyces capitatus. To our knowledge, only three cases of spondylodiscitis with this yeast have been described. Six months of voriconazole and liposomal amphotericin B treatment produced a complete resolution on CT and MRI imaging. However, the ongoing severe yeast infection prevented the planned bone marrow allograft.

show abstract

Infection à Geotrichum capitatum chez un patient neutropénique. À propos d'un cas et revue de la littérature

Cited by 21 publications

References 12 publications

Infection pulmonaire à Geotrichum capitatum à propos d’un cas et revue de la littérature

Infection pulmonaire à Geotrichum capitatum à propos d’un cas et revue de la littérature

Opportunistic infections in polymyositis and dermatomyositis

Cervical Spondylodiscitis Caused by Blastoschizomyces capitatus

Contact Info

Product

Resources

About