Infection and the Risk of Spontaneous Cervical Artery Dissection

Abstract

Background and Purpose-Several constitutional and environmental risk factors may be involved in the occurrence of spontaneous cervical artery dissection (SCAD). This work explored the association between recent infection and SCAD in an hospital-based case-control study. Methods-Forty-seven patients with SCAD and 52 with ischemic stroke from another cause were prospectively and consecutively recruited by 2 neurology departments. A specially designed questionnaire was used to assess the history of an acute infection that could have occurred within a month before the vascular event. Results-Acute infection was more frequent in patients with SCAD (31.9%) than in control subjects (13.5%) (crude odds ratio, 3.0; 95% confidence interval, 1.1 to 8.2; Pϭ0.032). This association was stronger in patients with multiple (odds ratio, 6.4) than single artery (odds ratio, 2.1) dissection. Conclusions-Recent infection is a risk factor and could be a trigger for SCAD. (Stroke. 2003;34:e79-e81.)

Dissecção espontânea cervical carotídea e verbal: estudo de 48 pacientes

“…Entretanto, como a investigação de hiper-homocisteinemia não foi realizada na maioria dos nossos pacientes, não foi possível concluir sua importância como fator de risco na nossa casuística. Infecção há menos de um mês da dissecção também tem sido sugerida como fator de risco principalmente nos casos multiarteriais 24 , mas essa informação não foi obtida na nossa série.…”

Dissecção espontânea das artérias carótidas e vertebrais em uma população multiétnica

“…Estudos anteriores demonstraram que até 32% dos pacientes com DEACV tiveram uma infecção recente 23 . A relação entre doenças auto-imunes e DEACV vem sendo recentemente discutida na literatura, particularmente a associação entre DEACV e doença tireoidiana 24 .…”

Subarachnoid Hemorrhage due to Vertebral Artery Dissection after Lung Resection

“…In regard to possible reasons for his VA dissection, one is pulmonary infection. 8) Histological findings demonstrated pneumonia and abscess formation in the resected lung. The other is hyperextension or torsion of his neck.…”

“…Underlying vascular disorders such as fibromuscular dysplasia and cystic medial necrosis, infections, trauma, hypertension, and oral contraceptives are reportedly associated with VA dissection. 3,8) The most commonly encountered factor is a wide variety of trauma to the head and neck. 4) Many reports have followed apparently trivial traumatic events, including performing yoga exercise, chiropractic manipulation, visiting a hairdresser, a fall during intoxication with alcohol, and even undergoing gastrofiberscopic examination under general anesthesia.…”