Infection Due to Saksenaea vasiformis Following a Spider Bite

Tormos, Esther Fernández; Izquierdo, María Ángeles Martínez; Sánchez-Artola, Beatriz; Aranzabal, Borja Limousin; Larraínzar-Garijo, Ricardo

doi:10.1016/j.jhsa.2018.08.020

Cited by 7 publications

(3 citation statements)

References 8 publications

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“…Probably Cachia et.al [38] in 2016 and Köse et.al [39] in 2020 reported the most similar case to ours, at least in location and initial local loxoscelism responses and complications. The first patient was a female with a bite on his thigh; she had a 2-month follow-up, and it is evidenced the chronic complication of a local wound and dermatological management in the future, but there was no further report on its evolution.…”

Section: Dayssupporting

confidence: 77%

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Lymphedema as Consequence of Loxosceles Brown Spider Bite: A Case Report and Literature Review

López-Montoya¹,

Zarate-Sánchez

Saenz-Ramirez

et al. 2022

IJTDH

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Introduction: Secondary lymphedema is defined as a chronic-progressive disease that causes rich protein edema of the limbs, this may be caused due to the damage or obstruction of lymphatic structures; complications associated with loxosceles spider bite may cause damage to the lymphatic system. Objective: To describe the clinical case of a patient with lower extremity lymphedema secondary to loxosceles' spider bite complications and to present a literature review on the topic. Case Presentation: A 24-year-old man received previous medical attention between 2020-and 2021 due to complications of a loxosceles brown spider bite. He arrived at our facilities in January 2022 to assess his case related to progressive volume leg increase and a chronic wound in the bitten site. After the clinical history analysis, physical examination, and a near-infrared lymphography study of the leg, damage to lymphatic structures was identified; secondary lymphedema was confirmed. It was possible to reverse and control the lymphedema volume and the wound evolved to complete closure. The case is presented along with a literature review on the topic. Conclusion: It is presented a case of lymphedema associated with a loxosceles brown spider bite, and successfully treated. Lymphedema related to a loxosceles spider bite and its complications is a clinical reality that might be underrecognized by scientific literature and clinicians; this condition should be properly studied and considered with adequate assessment strategies in patients after suffering the spider bite in extremities, especially in the mid and long-term.

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Section: Dayssupporting

confidence: 77%

“…Köse A.,et. al [39] 2020 Case report A 29-year-old female patient who had no history of illness was admitted to the emergency department. The patient reported that she had been bitten by a brown spider on the upper part of her left knee 6 days earlier.…”

Section: Monthsmentioning

confidence: 99%

Lymphedema as Consequence of Loxosceles Brown Spider Bite: A Case Report and Literature Review

López-Montoya¹,

Zarate-Sánchez

Saenz-Ramirez

et al. 2022

IJTDH

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“…Venoms enriched in PLD isoforms with low enzymatic and biological activities could explain lower toxicities in injured patients. The presence of certain comorbidities, such as diabetes, obesity, and allergies to other venom toxins, may be another explanation, as signs of loxoscelism are worse in these patients [ 7 , 74 ]. In addition, the age of victims seems to have an influence, as several studies have indicated greater severity of bites by Loxosceles in children, teenagers, and elderly victims [ 5 , 23 , 25 ].…”

Section: Final Considerationsmentioning

confidence: 99%

Systemic Loxoscelism, Less Frequent but More Deadly: The Involvement of Phospholipases D in the Pathophysiology of Envenomation

Gremski

Justa

Polli

et al. 2022

Toxins

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Bites of Loxosceles spiders can lead to a set of clinical manifestations called loxoscelism, and are considered a public health problem in many regions. The signs and symptoms of loxoscelism are divided into cutaneous and systemic forms. The former is more frequent and includes signs of envenoming at the bite site or neighboring regions. Systemic loxoscelism, although much less frequent, is associated with complications, and can even lead to death. It may include intravascular hemolysis, acute renal failure, and thrombocytopenia. Loxosceles venoms are enriched with phospholipases D (PLDs), which are a family of isoforms found at intra-species and inter-species levels. Under experimental conditions, these enzymes reproduce the main clinical signs of loxoscelism, including an exacerbated inflammatory response at the bite site and dermonecrosis, as well as thrombocytopenia, intravascular hemolysis, and acute renal failure. The role of PLDs in cutaneous loxoscelism was described over forty years ago, when studies identified and purified toxins featured as sphingomyelinase D. More recently, the production of recombinant PLDs and discoveries about their structure and mechanism has enabled a deeper characterization of these enzymes. In this review, we describe these biochemical and functional features of Loxosceles PLDs that determine their involvement in systemic loxoscelism.

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Clinical aspects, diagnosis and management of Loxosceles spider envenomation: literature and case review

et al. 2020

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Infection Due to Saksenaea vasiformis Following a Spider Bite

Cited by 7 publications

References 8 publications

Lymphedema as Consequence of Loxosceles Brown Spider Bite: A Case Report and Literature Review

Lymphedema as Consequence of Loxosceles Brown Spider Bite: A Case Report and Literature Review

Systemic Loxoscelism, Less Frequent but More Deadly: The Involvement of Phospholipases D in the Pathophysiology of Envenomation

Clinical aspects, diagnosis and management of Loxosceles spider envenomation: literature and case review

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