Infection following treatment of mandible fractures: the role of immunosuppression and polysubstance abuse

Preoperative Alcohol Consumption and Postoperative Complications

“…6,14,15,17,19,35,36,[42][43][44][45] The pooled RR from the adjusted results was substantially lower than the pooled RR from the unadjusted results and slightly lower than the overall pooled RR (Table 3). 6,14,15,17,19,35,36,[42][43][44][45] The pooled RR from the adjusted results was substantially lower than the pooled RR from the unadjusted results and slightly lower than the overall pooled RR (Table 3).…”

Timing for repair of mandible fractures

“…Patients with mandible fractures have a high rate of substance abuse and in the face of assault may not seek immediate medical care. In addition, patients with substance abuse are known to have an increased risk of infectious complications 9, 10…”

Impact of Diabetes on Fracture Healing

“…26 Diabetes impairs fracture healing of bone, including the mandible, hip, and long bones. 13,23,27,28 Clinical studies have reported delayed union or increased healing time in diabetic subjects compared with matched controls. 29e31 Long-bone fractures of streptozotocin-induced diabetic animals also exhibit changes consistent with impaired healing, including smaller calluses with decreased bone and reduced mechanical strength compared with those of controls.…”