Infection in Surgery: How to Manage the Surgical Wound

Foghetti, Domitilla

doi:10.1007/978-3-030-62116-2_4

Cited by 1 publication

(2 citation statements)

References 25 publications

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“…With secondary intention healing, wounds must heal from the bottom up, which can be slow and result in scar development [3,4]. Healing by tertiary intention, when surgical wounds are left exposed to heal by secondary intention, until any abscesses infection or when dehiscence or contaminated-dirty wounds occur [5].…”

Section: Introductionmentioning

confidence: 99%

“…Luteolin nanoparticles (3,4,5,7-tetrahydroxy flavone) is a natural dietary flavonoid, commonly present at high concentrations in several types of fruits, vegetables, and medicinal herbs [6].Luteolin nanoparticles was initially discovered in 1829 by Michel Eugène Chevreul, a French chemist who extracted luteolin nanoparticles in its pure state [7].Structurally, the presence of hydroxyl moieties at carbons 5, 7, 3, and 4 positions of the luteolin nanoparticles structure and the presence of the 2 -3 double bonds usually have different pharmacological benefits or effects [8].…”

Section: Introductionmentioning

confidence: 99%

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Evaluating the Effect of Topical Flavonoid Luteolin on Skin Wound Healing in Rabbits

Mhimed

Alsadoon²,

Taqa

2023

Egyptian Journal of Veterinary Sciences

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B ACKGROUND:The aim of this study was to evaluate effect of luteolin nanoparticles cream on wound healing in rabbit skin. Martial and Methods: Thirty male rabbits were used in this study. Wound in skin was induced in all rabbits and divided into 5 groups. Group 1: no wound carried out (negative control), Group2: (positive control) dressing wounds by cream only while Groups 3,4,5: dressing wounds by luteolin nanoparticles cream (1%, 2%, 4%), respectively. Treatment was repeated every day. The wound size, tissue type observation assessment were measured at 1 st , 3 th , 7 th days of the experimental procedure. Results: At 3 th day no significant difference between negative and positive control groups was observed but there are significantly difference between all treated groups of luteolin nanoparticles cream at (1%, 2%, 4%) in comparison to positive control and negative control groups . At day 7 there were significant difference in wounds size between groups treated with luteolin nanoparticles in different concentrations (9.3±1.3, 7.3±0.6 and 4.0±1.1),respectively and between negative control groups whereas no significant difference within groups treated with luteolin nanoparticles cream in 1%, 2% and 4% (9.3±1.3,7.3±0. 6 and 4.0±1.1 mm), respectively. Clinical finding of the tissue type that present in the wound showed that epithelization in all groups treated with luteolin nanoparticles in different concentrations in comparison to negative and positive control. Conclusions: Topical application luteolin nanoparticles cream in different concentrationsaccelerate skin wounds healing in rabbits.

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Section: Introductionmentioning

confidence: 99%