Infection of humans and animals with Echinococcus granulosus (G1 and G3 strains) and E. ortleppi in Southern Brazil

Rue, Mario Luiz de la; Takano, Keishi; Brochado, Joaquim F.; Costa, Carmem V.; Soares, Antônio Gomes; Yamano, Kimiaki; Yagi, Kinpei; Katoh, Yoshinobu; Takahashi, Ken­ichi

doi:10.1016/j.vetpar.2010.11.018

Cited by 57 publications

(39 citation statements)

References 24 publications

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“…From the epidemiological standpoint, it is very likely that livestock movements account for the introduction of E. granulosus ( s.s .) (G1) from known endemic areas in southern Brazil [10, 11, 53, 54]. …”

Section: Discussionmentioning

confidence: 99%

First molecular identification of Echinococcus vogeli and Echinococcus granulosus (sensu stricto) G1 revealed in feces of domestic dogs (Canis familiaris) from Acre, Brazil

et al. 2017

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Background Echinococcus granulosus (sensu lato) (s.l.) and Echinococcus vogeli are causative agents of chronic zoonotic diseases such as cystic and polycystic echinococcosis, respectively. In Brazil, polycystic echinococcosis has a restricted geographical distribution in the North Region, while cystic echinococcosis is observed in the South Region. Domestic dogs (Canis familiaris) fed with raw viscera represent a risk factor for E. granulosus (s.l.) infection in the South Region. Although this practice is frequent, it remains unclear whether domestic dogs are infected with E. vogeli in the state of Acre, located in the Amazon basin in the North Region of Brazil. The aim of this study was to investigate this gap in the polycystic echinococcosis epidemiology.MethodsSixty-five fecal samples were collected from the ground in five municipalities (Sena Madureira, n = 14; Rio Branco, n = 06; Bujari, n = 06; Xapuri, n = 30; and Epitaciolândia, n = 09) located in the state of Acre, northern Brazil. The samples were screened for parasites by copro-PCR using the cox1 gene associated with automated sequencing.Results Echinococcus vogeli was molecularly confirmed in a sample from Sena Madureira and E. granulosus (sensu stricto) (s.s.) (G1) in a sample from Rio Branco.ConclusionsThese findings indicate that molecular assays are useful in typing Echinococcus taxa from fecal samples of dogs in northern Brazil. The present study is the first molecular record of E. vogeli in domestic dogs found in the state of Acre, reinforcing their role as a source of infection for humans. Because E. granulosus (s.s.) (G1) was detected for the first time in the North Region, from the epidemiological standpoint this finding is highly relevant, because it expands the known geographical distribution, which was previously restricted to the South Region of Brazil.

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Section: Discussionmentioning

confidence: 99%

First molecular identification of Echinococcus vogeli and Echinococcus granulosus (sensu stricto) G1 revealed in feces of domestic dogs (Canis familiaris) from Acre, Brazil

et al. 2017

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“…[48][49][50][51][52][53][54][55] For the first time in Iran, Sharbatkhori and others 30 reported the occurrence of the G3 genotype in camels from the Isfahan Province (central Iran). This was a global first for the identification of the G3 genotype in this host.…”

Section: Discussionmentioning

confidence: 99%

Genetic Characterization of Echinococcus granulosus from a Large Number of Formalin-Fixed, Paraffin-Embedded Tissue Samples of Human Isolates in Iran

Rostami¹,

Torbaghan²,

Dabiri³

et al. 2015

The American Society of Tropical Medicine and Hygiene

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Abstract. Cystic echinococcosis (CE), caused by the larval stage of Echinococcus granulosus, presents an important medical and veterinary problem globally, including that in Iran. Different genotypes of E. granulosus have been reported from human isolates worldwide. This study identifies the genotype of the parasite responsible for human hydatidosis in three provinces of Iran using formalin-fixed paraffin-embedded tissue samples. In this study, 200 formalin-fixed paraffin-embedded tissue samples from human CE cases were collected from Alborz, Tehran, and Kerman provinces. Polymerase chain reaction amplification and sequencing of the partial mitochondrial cytochrome c oxidase subunit 1 gene were performed for genetic characterization of the samples. Phylogenetic analysis of the isolates from this study and reference sequences of different genotypes was done using a maximum likelihood method. In total, 54.4%, 0.8%, 1%, and 40.8% of the samples were identified as the G1, G2, G3, and G6 genotypes, respectively. The findings of the current study confirm the G1 genotype (sheep strain) to be the most prevalent genotype involved in human CE cases in Iran and indicates the high prevalence of the G6 genotype with a high infectivity for humans. Furthermore, this study illustrates the first documented human CE case in Iran infected with the G2 genotype.

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“…Cattle infected by this specific species normally develop hydatid cysts with fertility rates close to 100% (Balbinotti et al, 2012;Kamenetzky et al, 2002). In addition, E. ortleppi has been identified as the etiological agent of CE in four human autochthonous cases: one in Mexico (Maravilla et al, 2004), one in Brazil (de la Rue et al, 2011) and two in Argentina (Guarnera et al, 2004;Kamenetzky et al, 2002). These findings suggest that cattle may sporadically act as epidemiological reservoir of human disease.…”

Section: Molecular Epidemiology Of Cystic Echinococcosis In Productiomentioning

confidence: 96%

A review of the global prevalence, molecular epidemiology and economics of cystic echinococcosis in production animals

Cardona

Carmena

2013

Veterinary Parasitology

198

143

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Infection of humans and animals with Echinococcus granulosus (G1 and G3 strains) and E. ortleppi in Southern Brazil

Cited by 57 publications

References 24 publications

First molecular identification of Echinococcus vogeli and Echinococcus granulosus (sensu stricto) G1 revealed in feces of domestic dogs (Canis familiaris) from Acre, Brazil

First molecular identification of Echinococcus vogeli and Echinococcus granulosus (sensu stricto) G1 revealed in feces of domestic dogs (Canis familiaris) from Acre, Brazil

Genetic Characterization of Echinococcus granulosus from a Large Number of Formalin-Fixed, Paraffin-Embedded Tissue Samples of Human Isolates in Iran

A review of the global prevalence, molecular epidemiology and economics of cystic echinococcosis in production animals

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