Infections in diabetic foot ulcers

Treatment of musculoskeletal infections of the foot in patients with diabetes

“…Most mild, acute infections, particularly those in antibiotic-naïve patients, are usually monomicrobial, caused by aerobic Gram-positive cocci [17,52]. Between 50 and 80% of infections are caused either by coagulase-positive ornegative staphylococci [52][53][54][55][56].…”

“…Between 50 and 80% of infections are caused either by coagulase-positive ornegative staphylococci [52][53][54][55][56]. Methicillin-resistant Staphylococcus aureus (MRSA) has become increasingly prevalent in diabetic foot wounds [56].…”

“…Methicillin-resistant Staphylococcus aureus (MRSA) has become increasingly prevalent in diabetic foot wounds [56]. Of the staphylococcus strains, 15 to 40% are MRSA and are frequently isolated from patients who have previously received antibiotic Musculoskeletal infections of the diabetic foot -REVIEW therapy, were treated in hospital, or at chronic care facilities [52,54,57]. MRSA colonization had an adverse effect on wound healing [54,58].…”

“…MRSA colonization had an adverse effect on wound healing [54,58]. Streptococci are involved in approximately 10 to 40% of all cases [52][53][54][55], often as part of a polymicrobial infection [53,54]. Necrotizing fasciitis has classically been connected with streptococci.…”

“…Gram-positive cocci remain the most frequently isolated organisms in the more severe infections; Gram-negative aerobic bacilli accounted for less than a third of the total microorganisms [52][53][54][55]. Gram-negative bacilli are found in many patients with chronic or previously treated infections [31].…”