Infections of the Central Nervous System in Returning Travelers and Immigrants

Thompson, Haley; Thakur, Kiran T.

doi:10.1007/s11908-017-0594-5

Cited by 12 publications

(4 citation statements)

References 55 publications

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“…Migrants, refugees, and tourists face comparable risks related to travel; however, the former two are even made more vulnerable by abject living environments, deprivation and poor hygiene whilst migrating, and halted vaccination programs during times of war, conflict, or social unrest [81,82]. Due to civil war, polio vaccination coverage in Syria decreased from 99% in 2010 to 68% in 2012 [68].…”

Section: Vulnerable Populationsmentioning

confidence: 99%

Addressing vaccine-preventable encephalitis in vulnerable populations

Piamonte

Easton²,

Wood

et al. 2023

Current Opinion in Neurology

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Purpose of reviewVaccinations have been pivotal in lowering the global disease burden of vaccine-preventable encephalitides, including Japanese encephalitis, tick-borne encephalitis, measles encephalitis, and rabies encephalitis, among others. Recent findingsPopulations vulnerable to vaccine-preventable infections that may lead to encephalitis include those living in endemic and rural areas, military members, migrants, refugees, international travelers, younger and older persons, pregnant women, the immunocompromised, outdoor, healthcare and laboratory workers, and the homeless. There is scope for improving the availability and distribution of vaccinations, vaccine equity, surveillance of vaccine-preventable encephalitides, and public education and information.

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Section: Vulnerable Populationsmentioning

confidence: 99%

Addressing vaccine-preventable encephalitis in vulnerable populations

Piamonte

Easton²,

Wood

et al. 2023

Current Opinion in Neurology

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show abstract

“…A travel-associated infectious disease was considered an important differential diagnosis from the very first moment due to the presented neurological symptoms associated with a journey abroad [9]. All relevant pathogens were examined after an evaluation of the potential exposure risk [10].…”

Section: Discussionmentioning

confidence: 99%

Travel-associated neurological disease terminated in a postmortem diagnosed atypical HSV-1 encephalitis after high-dose steroid therapy – a case report

Osterman

Ruf²,

Domingo

et al. 2020

BMC Infect Dis

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Background: Human encephalitis can originate from a variety of different aetiologies, of which infection is the most common one. The diagnostic work-up is specifically challenging in patients with travel history since a broader spectrum of unfamiliar additional infectious agents, e. g. tropical disease pathogens, needs to be considered. Here we present a case of encephalitis of unclear aetiology in a female traveller returning from Africa, who in addition developed an atypical herpes simplex virus (HSV) encephalitis in close temporal relation with high-dose steroid treatment. Case presentation: A previously healthy 48-year-old female presented with confusion syndrome and impaired vigilance which had developed during a six-day trip to The Gambia. The condition rapidly worsened to a comatose state. Extensive search for infectious agents including a variety of tropical disease pathogens was unsuccessful. As encephalitic signs persisted despite of calculated antimicrobial and antiviral therapy, high-dose corticosteroids were applied intravenously based on the working diagnosis of an autoimmune encephalitis. The treatment did, however, not improve the patient's condition. Four days later, bihemispheric signal amplification in the insular and frontobasal cortex was observed on magnetic resonance imaging (MRI). The intracranial pressure rapidly increased and could not be controlled by conservative treatment. The patient died due to tonsillar herniation 21 days after onset of symptoms. Histological examination of postmortem brain tissue demonstrated a generalized lymphocytic meningoencephalitis. Immunohistochemical reactions against HSV-1/2 indicated an atypical manifestation of herpesviral encephalitis in brain tissue. Moreover, HSV-1 DNA was detected by a next-generation sequencing (NGS) metagenomics approach. Retrospective analysis of cerebrospinal fluid (CSF) and serum samples revealed HSV-1 DNA only in specimens one day ante mortem.

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“…La neurocisticercosis (NCC) es una entidad endémica en América Central y del Sur, siendo reconocida como la infección parasitaria más común del sistema nervioso central y principal causa de epilepsia 25 . Revisiones sistemáticas la describen como causa entre el 30 a 40% de los pacientes epilépticos en regiones endémicas 26 .…”

Section: Neurocisticercosisunclassified

Patologías del niño inmigrante en la Unidad de Cuidados Intensivos

T.¹,

M.²,

F.³

et al. 2020

Rev Chil Pediatr

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Cada vez es más frecuente la atención médica en la Unidad de Cuidados Intensivos (UCI) de niños o adolescentes inmigrantes como también de aquellos nacidos en nuestro país con padres en tal condición. Esto ha ocasionado, en la actualidad, que el equipo de salud se deba enfrentar con problemas diagnósticos derivados del escaso conocimiento de condiciones genéticas propias de esta población y/o el desarrollo de diversas patologías infrecuentes en nuestro país, algunas resultantes de su condición sanitaria. En esta revisión se abordan diversos aspectos de la patología hematológica, infecciosa, parasitaria, respiratoria y cardiovascular, todos tópicos relevantes de conocer durante su estadía en la UCI. Es un deber del equipo de salud actualizarse sobre patologías de baja prevalencia en nuestro país, algunas de ellas muy poco conocidas hasta hace una década, pero que, actualmente, están cada vez más presentes en las UCI del sistema de salud público chileno.

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Infections of the Central Nervous System in Returning Travelers and Immigrants

Cited by 12 publications

References 55 publications

Addressing vaccine-preventable encephalitis in vulnerable populations

Addressing vaccine-preventable encephalitis in vulnerable populations

Travel-associated neurological disease terminated in a postmortem diagnosed atypical HSV-1 encephalitis after high-dose steroid therapy – a case report

Patologías del niño inmigrante en la Unidad de Cuidados Intensivos

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