Infectious and Presumed Noninfectious Endophthalmitis After Intravitreal Triamcinolone Acetonide Injection

Abstract

Bacterial endophthalmitis after intravitreal triamcinolone acetonide injection may present in an atypical, relatively delayed manner with decreased vision but no pain or redness. Presumed noninfectious endophthalmitis presents within 2 days after the injection, may be accompanied by discomfort, and has a hypopyon that may be the triamcinolone material itself or a sterile inflammatory reaction. In these eyes, the hypopyon and symptoms quickly resolve without treatment.

Intravitreal triamcinolone acetonide vs bevacizumab for treatment of macular oedema due to central retinal vein occlusion

“…For these reasons, intravitreal bevacizumab may be an attractive alternative therapeutic option for phakic patients and steroid responders because it provides visual acuity improvement and macular thickness reduction without the side effects of ocular hypertension and cataract progression. Additional injection-related complications reported in other studies, such as conjunctival ulceration, 36 retinal detachment, 37 infectious, or non-infectious endophthalmitis, [37][38][39] were not observed in our study.…”

Intravitreal triamcinolone acetonide vs bevacizumab for treatment of macular oedema secondary to branch retinal vein occlusion

“…To avoid the above complications mentioned in triamcinolone acetonide injection, intravitreal bevacizumab may be an attractive alternative therapeutic option for phakic patients and steroid responders because it provides visual acuity improvement and restoration of retinal anatomy without the side effects of ocular hypertension and cataract progression, and the absence of any inflammation suggests that even repeated injections are well tolerated. Additional injection-related complications reported in other studies, such as conjunctival ulceration, 47 retinal detachment, 48 infectious or non-infectious endophthalmitis, [48][49][50] were not observed in our study.…”

Intravitreal triamcinolone improves vision in eyes with chronic diabetic macular oedema refractory to laser photocoagulation

“…17,18 Like Martidis and Jonas et al, we did not encounter this complication in our group of patients, however, only three of our eyes have received a second injection to date. With increasing follow-up, we anticipate a rise in the number of patients requiring repeat injections due to the recurrence of macular oedema.…”