Infectious complications in compound mandibular fractures undergoing a delayed surgical intervention – a prospective observational study

Sundheepkumar, V.; Saravanan, R.; Krishnan, Balasubramanian

doi:10.1016/j.bjoms.2023.03.008

Cited by 3 publications

(1 citation statement)

References 24 publications

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“…Fractures of the dentate part of the mandible are prone to infections, especially as a postoperative complication of surgical management [ 1 – 4 ]. However, sometimes the fracture is already clinically infected at the time of surgery.…”

Section: Introductionmentioning

confidence: 99%

Surgical treatment of clinically infected mandibular fractures

Oksa,

Haapanen,

Kannari

et al. 2024

Oral Maxillofac Surg

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Purpose To clarify reasons for infections, surgical techniques, and occurrence of postoperative surgical site complications in infected mandibular fractures. Methods Patients with clinically infected mandibular fracture of the dentate part without preceding surgery were studied retrospectively. Clinical infection was defined to occur if pus, abscess, or a fistula in the fracture area was present. Patient-, fracture-, and surgery-related variables were evaluated, and predictors for postoperative complications were analysed. Results Of 908 patients with surgically treated fracture in the dentate part of the mandible, 41 had infected fracture at the time of surgery (4.5%). Of these patients, 46.3% were alcohol or drug abusers. Median delay from injury to surgery was 9 days. Patient-related factors were the most common cause for delayed surgery (n = 30, 73.2%), followed by missed diagnosis by a health care professional (n = 8, 19.5%). Twenty-two fractures were treated via extraoral approach (53.7%) and the remaining 19 intraorally (46.3%). Postoperative surgical site complications were found in 13 patients (31.7%), with recurrent surgical site infections predominating. Notable differences between total complication rates between intraoral and extraoral approaches were not detected. Secondary osteosynthesis for non-union was conducted for one patient treated intraorally. Conclusions Postoperative surgical site complications are common after treatment of infected mandibular fractures, and these occur despite the chosen surgical approach. Infected mandibular fractures heal mainly without bone grafting, and non-union is a rare complication. Due to the high complication rate, careful perioperative and postoperative care is required for these patients.

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Section: Introductionmentioning

confidence: 99%

Surgical treatment of clinically infected mandibular fractures

Oksa,

Haapanen,

Kannari

et al. 2024

Oral Maxillofac Surg

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Factors contributing to non-union amongst dentate mandibular fractures treated by load-sharing miniplate osteosynthesis: a case-control study

Aditya,

Krishnan

2024

British Journal of Oral and Maxillofacial Surgery

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The Effect of Duration of Antibiotic Prophylaxis on Infections Following Open Reduction and Internal Fixation of Mandibular Fractures: A Prospective Randomized Clinical Trial

Rikhotso,

Mohotlhoane

2023

Journal of Craniofacial Surgery

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Aim: To evaluate the benefits of a long-term prophylactic antibiotic regimen following treatment of fractured mandibles with open reduction and internal fixation. Material and Methods: A prospective, randomized controlled trial was undertaken at Wits Oral Health Centre. Patients with mandibular fractures who were managed with open reduction and internal fixation using miniplates were randomized into 2 groups. The control group, the perioperative antibiotic (POA) group, was composed of patients who received intravenous (IV) antibiotic cover intraoperatively and a further 3 IV doses 24 hours postoperatively. The study group, the extended postoperative antibiotic (EPOA), was composed of patients who received similar doses as the control group but with an additional 5 days of oral antibiotics upon discharge. The patients were then evaluated for evidence of infection 1, 4, and 6 weeks postoperatively. Results: A total of 77 patients were included in the study, 41 in the POA and 36 in the EPOA groups. Fourteen patients had evidence of infection noted within the 6-week follow-up period (10 in the POA and 4 in the EPOA groups). Statistical analysis with the Pearson Chi-square and Student t test showed no statistically significant difference (P=0.399) between POA and EPOA groups. There were no significant differences between the groups with respect to site and etiology of fracture, duration of operation, and presence of infection (P>0.05) during the 6-week review period. Conclusions: The extended use of antibiotic prophylaxis when managing mandibular fractures with open reduction and internal fixation offers no additional benefit in reducing postoperative infections.

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Infectious complications in compound mandibular fractures undergoing a delayed surgical intervention – a prospective observational study

Cited by 3 publications

References 24 publications

Surgical treatment of clinically infected mandibular fractures

Surgical treatment of clinically infected mandibular fractures

Factors contributing to non-union amongst dentate mandibular fractures treated by load-sharing miniplate osteosynthesis: a case-control study

The Effect of Duration of Antibiotic Prophylaxis on Infections Following Open Reduction and Internal Fixation of Mandibular Fractures: A Prospective Randomized Clinical Trial

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