Infectious Complications of Solid Organ Transplantations

Human Microbiota Characterization in the Course of Renal Transplantation

“…All three sample types, especially urine and rectal samples, were more similar in the weighted UniFrac analysis, suggesting A 4562 147 3654 207 2997 301 3477 239 B 4573 135 3343 159 3504 224 3787 173 C 5083 112 3843 151 5576 366 4913 243 Total 4652 135 3599 190 3596 291 3768 220 A, collected immediately before transplantation; B, collected 1 month (AE1 week); C, 6 (AE1) months after transplantation; OTU, operational taxonomic unit. 1 Average read numbers per sample. 2 Average OTU numbers per sample.…”

“…The clinical outcomes of renal allograft recipients have improved in part because of a decline in infection-related morbidity and mortality. Prior to 1980, 60% of kidney transplant recipients developed at least one serious infection during the first year posttransplant, with mortality rates approaching 50% (1). Although the current infection-related 1-year mortality has been reduced to <5%, infectious complications remain serious threats (1).…”

“…Prior to 1980, 60% of kidney transplant recipients developed at least one serious infection during the first year posttransplant, with mortality rates approaching 50% (1). Although the current infection-related 1-year mortality has been reduced to <5%, infectious complications remain serious threats (1). Since the outcome of transplantation is linked to prevention, early diagnosis, specific timely treatment of infectious complications and a better understanding of factors that impact risk for posttransplant infection are mandatory.…”

Comparison of Two Microdilution Methods for Testing Susceptibility of Candida spp. to Voriconazole

“…The incidence of invasive mycosis in immunocompromised or surgically treated patients has risen in recent years (20). Growing primary and secondary resistance to classical antifungal agents has led to the need to develop new agents (7) such as voriconazole (3).…”

Hepatic abscesses after liver transplantation secondary to traumatic intrahepatic bile duct injuries in a cadaveric allograft donor

“…Given that up to 67% of orthotopic liver transplantations will go on to develop at least one major infection post-operatively the causes of such a presentation are quite numerous [17]. However if a donor liver is known to have suffered physical trauma as part of the process leading to organ donation, consideration should be given to the presence of liver abscesses secondary to intrahepatic duct injury and biloma formation.…”