2022
DOI: 10.1007/s44174-022-00035-y
|View full text |Cite
|
Sign up to set email alerts
|

Infectious Diseases Impact on Biomedical Devices and Materials

Abstract: Infectious diseases and nosocomial infections may play a significant role in healthcare issues associated with biomedical materials and devices. Many current polymer materials employed are inadequate for resisting microbial growth. The increase in microbial antibiotic resistance is also a factor in problematic biomedical implants. In this work, the difficulty in diagnosing biomedical device-related infections is reviewed and how this leads to an increase in microbial antibiotic resistance. A conceptualization … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
4

Citation Types

0
4
0

Year Published

2023
2023
2024
2024

Publication Types

Select...
5

Relationship

0
5

Authors

Journals

citations
Cited by 5 publications
(4 citation statements)
references
References 79 publications
0
4
0
Order By: Relevance
“…However, the biofilm EPS layer effectively impedes the diffusion of antibiotics into the matrix, preventing eradication. The high tolerance of antibiotics from these microorganisms has led to the overuse and inevitable development of resistance to these treatments. , …”
Section: Introductionmentioning
confidence: 99%
See 2 more Smart Citations
“…However, the biofilm EPS layer effectively impedes the diffusion of antibiotics into the matrix, preventing eradication. The high tolerance of antibiotics from these microorganisms has led to the overuse and inevitable development of resistance to these treatments. , …”
Section: Introductionmentioning
confidence: 99%
“…The high tolerance of antibiotics from these microorganisms has led to the overuse and inevitable development of resistance to these treatments. 3,7 To counter these limitations, research has been directed toward developing antimicrobial biomaterials that can resist bacterial infections without systemic antibiotics. These strategies include the incorporation of active biocidal molecules, such as silver nanoparticles, 8,9 antimicrobial peptides, 10,11 antibiotics, 12,13 nitric oxide (NO), 11,14,15 bacteriophages, 16,17 and surface modifications, such as altered surface wettability 18,19 and texturing.…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…However, the implantation of these foreign materials into the human body poses unavoidable risks. 1 According to the US Center for Prostheses Infection, biomedical devices are implicated in 50% of annual nosocomial infections, making them a major concern in healthcare systems worldwide, with serious clinical and economic burden. 2 These infections are typically generated by microbial colonization mainly as a complex slimy “biofilm” leading to both clinical illness and device dysfunction.…”
Section: Introductionmentioning
confidence: 99%