Infectious mononucleosis

Antibiotic Induced Cutaneous Rash in Infectious Mononucleosis: Overview of the Literature

“…The use of antibiotics is considered mostly unnecessary and is a consequence of misdiagnosis rather than the presence of a concomittant actual bacterial infection [9]. Although patients suffering from IM usually present the classic features, many of them are treated as bacterial infection.…”

“…Antibiotics: drugs causing rash with the highest incidence within IM There are some studies on the usefulness of antiviral, corticosteroid and anaerobic antibacterial (metronidazole) treatments in IM, however the generally accepted therapy is antipyretic and analgetic drugs, enough hydration and rest [4,[9][10][11]. The use of antibiotics is considered mostly unnecessary and is a consequence of misdiagnosis rather than the presence of a concomittant actual bacterial infection [9].…”

Two heterozygous Cav3.2 channel mutations in a pediatric chronic pain patient: recording condition-dependent biophysical effects

“…Infectious mononucleosis is a non-genetic syndrome whose major symptoms include fever, pharyngitis, and cervical lymphadenopathy, and it is caused by the Epstein Barr virus in 90 % of the cases [31]. Most symptoms tend to disappear in 2 to 4 weeks, although complications, including neurological disorders, can occur.…”

“…Most symptoms tend to disappear in 2 to 4 weeks, although complications, including neurological disorders, can occur. The incidence of neurologic complications from infectious mononucleosis in the literature range from 0.3 % to 7.3 % and include encephalitis, seizures, optic neuritis, facial palsy, and Guillain-Barré syndrome among others [31][32][33]. Although most of the neurologic complications from viral infections are acute, it is conceivable that a combination of the mutations in the susceptibility gene CACNA1H and the patient's viral infection combined triggered persistent changes in Cav3.2 channel function, thus giving rise to epilepsy and pain syndrome.…”

No new evidence to support the routine use of steroids in the treatment of infectious mononucleosis

“…Over 90% of cases are caused by the Epstein-Barr virus, a subclinical infection in childhood, to which 95% of the population have seroconverted by adolescence 1. Infection after this time will result in IM, a more severe illness than bacterial tonsillitis 2.…”