Infectious syphilis in young heterosexuals: responding to an evolving epidemic

Simms, Ian; Bell, Gill; Hughes, Gwenda

doi:10.1258/ijsa.2011.011206

Cited by 12 publications

(8 citation statements)

References 15 publications

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“…However, a significant proportion of syphilis cases are diagnosed late [13]. Due to comprehensive antenatal screening for syphilis infection in the UK, cases of congenital syphilis remain rare, although reported cases have been increasing in recent years [45,46].…”

Section: • • Syphilismentioning

confidence: 99%

The Epidemiology of Sexually Transmitted Infections in the UK: Impact of Behavior, Services and Interventions

Hughes

Field

2015

Future Microbiol.

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Sexually transmitted infections (STIs) are a major public health concern. The UK has some of the most advanced STI surveillance systems globally. This article uses national surveillance data to describe remarkable changes in STI epidemiology in the UK over the last century and explores the behavioral and demographic shifts that may explain these trends. The past 10 years have seen considerable improvements in STI service provision and the introduction of national public health interventions. However, sexual health inequalities persist and men who have sex with men, young adults and black ethnic minorities remain a priority for interventions. Technological advances in testing and a shift in sexual health service commissioning arrangements will present both opportunities and challenges in future.

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Section: • • Syphilismentioning

confidence: 99%

The Epidemiology of Sexually Transmitted Infections in the UK: Impact of Behavior, Services and Interventions

Hughes

Field

2015

Future Microbiol.

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“…The epidemic has been focused on infection in white MSM aged 25–34, many of whom having HIV co-infection and high numbers of sexual partners 1 2. Similar characteristics were seen in localised clusters although some centred on young, socially vulnerable heterosexuals 2 4. The detection of clusters has relied on the vigilance of local sexual health and public health professionals, but since effective control is dependent on early identification and case management, methods are required to systematically identify and assess emerging sexual health challenges.…”

Section: Introductionmentioning

confidence: 96%

Identifying and interpreting spatiotemporal variation in diagnoses of infectious syphilis among men, England: 2009 to 2013

Petersen¹,

Gibin²,

Sile

et al. 2016

Sex Transm Infect

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“…Stage of infection was recorded for 10 mothers, six of whom presented with primary syphilis, three with secondary and one with early latent syphilis. All mothers diagnosed with syphilis were managed according to British Association of Sexual Health and HIV Guidelines and many were the subject of further investigations by local Health Protection Units . The social circumstances of mothers varied and included injecting drug use, sex work and imprisonment, and some had experienced difficulty accessing healthcare due to cultural barriers.…”

Section: Resultsmentioning

confidence: 99%

The incidence of congenital syphilis in the United Kingdom: February 2010 to January 2015

Simms

Tookey

Goh

et al. 2016

BJOG

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Objective To estimate the incidence of congenital syphilis in the UK. Design Prospective study. Setting and population United Kingdom. Methods Children born between February 2010 and January 2015 with a suspected diagnosis of congenital syphilis were reported through an active surveillance system. Main outcome measures Number of congenital syphilis cases and incidence. Results For all years, reported incidence was below the WHO threshold for elimination (<0.5/1000 live births). Seventeen cases (12 male, five female) were identified. About 50% of infants (8/17) were born preterm (<37 weeks' gestation): median birthweight 2000 g (865–3170 g). Clinical presentation varied from asymptomatic to acute disease, including severe anaemia, hepatosplenomegaly, rhinitis, thrombocytopaenia, skeletal damage, and neurosyphilis. One infant was deaf and blind. Median maternal age was 20 years (17–31) at delivery. Where maternal stage of infection was recorded, 6/10 had primary, 3/10 secondary and 1/10 early latent syphilis. Most mothers were white (13/16). Country of birth was recorded for 12 mothers: UK (n = 6), Eastern Europe (n = 3), Middle East (n = 1), and South East Asia (n = 2). The social circumstances of mothers varied and included drug use and sex work. Some experienced difficulty accessing health care. Conclusion The incidence of congenital syphilis is controlled and monitored by healthcare services and related surveillance systems, and is now below the WHO elimination threshold. However, reducing the public health impact of this preventable disease in the UK is highly dependent on the successful implementation of WHO elimination standards across Europe. Tweetable abstract Congenital syphilis incidence in the UK is at a very low level and well below the WHO elimination threshold.

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Infectious syphilis in young heterosexuals: responding to an evolving epidemic

Cited by 12 publications

References 15 publications

The Epidemiology of Sexually Transmitted Infections in the UK: Impact of Behavior, Services and Interventions

The Epidemiology of Sexually Transmitted Infections in the UK: Impact of Behavior, Services and Interventions

Identifying and interpreting spatiotemporal variation in diagnoses of infectious syphilis among men, England: 2009 to 2013

The incidence of congenital syphilis in the United Kingdom: February 2010 to January 2015

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