Infectious Tenosynovitis (Viral Arthritis): Characterization of a Connecticut Viral Isolant as a Reovirus and Evidence of Viral Egg Transmission by Reovirus-Infected Broiler Breeders

Heide, L. van der; Kalbac, M.

doi:10.2307/1589180

Cited by 65 publications

(28 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Only one avian reovirus in our study had a sequence identical to the well-known reovirus strain S1133 originally isolated from a tenosynovitis case [15]. Vaccination against reovirus infection is mostly performed using strain S1133 [18] or 1733, a strain related to both tenosynovitis and stunting [11].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Classification of Dutch and German avian reoviruses by sequencing the ? C protein

Kant¹,

Balk

Born

et al. 2003

Vet. Res.

View full text Add to dashboard Cite

-We have amplified, cloned and sequenced (part of) the open reading frame of the S1 segment encoding the σ C protein of avian reoviruses isolated from chickens with different disease conditions in Germany and The Netherlands during 1980 up to 2000. These avian reoviruses were analysed phylogenetically and compared with sequences of avian reoviruses in the Genbank database. The avian reoviruses could be grouped in 5 different genotyping clusters and this classification was identical when the sequences were compared of the 5' end, the 3' end or the whole open reading frame of the σ C protein. Therefore sequencing of either part of the gene encoding the σ C protein seems to be reliable for classification. We were unable to identify a correlation between σ C sequences of the avian reoviruses and the disease condition they were isolated from. The sequences found in The Netherlands and in Germany are, like those in Taiwan, more dispersed than the known avian reovirus σ C sequences in the USA and Australia. We did not establish temporal or geographic differences in the avian reoviruses studied. avian reovirus / malabsorption syndrome / tenosynovitis / σ C gene / genotype

show abstract

Section: Discussionmentioning

confidence: 99%

“…These sequences were compared with known sequences of ARVs S1133 [15], 1733 [12], RAM-1 [6,7] and SOM4 [5,6]. Sequences of ARVs that were submitted to GenBank by Duncan in 2000 and by Liu et al in 2000 and in 2001, were also used for comparison (Tab.…”

Section: Alignment and Analysis Of Deduced Amino Acid Sequencesmentioning

confidence: 99%

Classification of Dutch and German avian reoviruses by sequencing the ? C protein

Kant¹,

Balk

Born

et al. 2003

Vet. Res.

View full text Add to dashboard Cite

show abstract

“…ARV NLI20 98M and NLI19 97M were isolated from the intestinal contents of MAS affected chickens in the field. We also used two tenosynovitis-associated ARVs: S1133 [26] and a Dutch field strain NLA13 96T, isolated at the Animal Health Service, Deventer, The Netherlands. All ARVs were propagated in chicken embryo liver cells (CELC).…”

Section: Virusesmentioning

confidence: 99%

Enteropathogenicity of Dutch and German avian reoviruses in SPF white leghorn chickens and broilers

Songserm

Roozelaar²,

Kant³

et al. 2003

Vet. Res.

View full text Add to dashboard Cite

-The enteropathogenicity of avian reoviruses (ARVs), isolated from chickens affected with malabsorption syndrome (MAS) from The Netherlands and Germany was studied. In the first trial seven different ARVs isolated from MAS cases were inoculated in 1-day-old specific pathogenic free (SPF) white leghorns. The pathogenicity was compared with 2 ARVs isolated from cases of tenosynovitis, namely reference strain S1133 and a Dutch strain. Although a difference in the severity of the clinical disease was observed, all reoviruses could induce vacuolar degeneration and sloughing of the epithelium of the small intestine at day 2 post inoculation (PI) till day 7 PI. Two Dutch and one German ARV derived from MAS causing the most severe intestinal lesions at day 2 PI, were further studied in the second trial using SPF broilers. These reoviruses did not cause weight gain depression in the broilers although lesions in the small intestine were present from day 1 up to day 4 PI and were more severe than in the white leghorn chickens. In one of the inoculated groups apical denuded villi were already present at day 1 PI. At day 7 PI the small intestine of the infected broilers appeared to be normal. Reovirus antigen was detected in the cytoplasm of the enterocytes at the tip and middle section of the affected villi both in layers and in broilers. To study the role of intestinal CD4 + and CD8 + T-cells and macrophages/monocytes in the pathogenesis of ARV, the numbers of these cells of the jejunal villi of one infected and the control broiler groups were compared. CD4 + T-cells were detected in low numbers and only in the infected broiler group at day 14 PI. The numbers of CD8 + T-cells and macrophages/monocytes were significantly higher in the infected broiler group than in the control broiler group at day 7 and 14 PI and at day 7 PI respectively. Our study indicates that the reovirus alone cannot induce intestinal lesions as found in MAS chickens. Moreover, CD8 + T-cells may play a major role in the pathogenesis and or reovirus clearance in the small intestine. malabsorption syndrome / runting-stunting syndrome / reovirus / enteropathogenicity / chicken

show abstract

“…Antibody against reovirus was assayed with the agar gel precipitation test (AGP). The antigen was a homogenised suspension of chorioallantoic membranes (CAM) infected with the S-1133 strain (Van der Heide and Kalbac, 1975) harvested 3 to 5 days after CAM infection of specific pathogen free (SPF) eggs. Antibody was demonstrated irregularly in a small proportion of the birds, indicating a low grade reovirus infection.…”

Section: Experimental Birds and Housingmentioning

confidence: 99%

Investigations into the role of reovirus in the malabsorption syndrome

Kouwenhoven¹,

Vertommen²,

Goren³

1988

Avian Pathology

View full text Add to dashboard Cite

Infectious Tenosynovitis (Viral Arthritis): Characterization of a Connecticut Viral Isolant as a Reovirus and Evidence of Viral Egg Transmission by Reovirus-Infected Broiler Breeders

Cited by 65 publications

References 7 publications

Classification of Dutch and German avian reoviruses by sequencing the ? C protein

Classification of Dutch and German avian reoviruses by sequencing the ? C protein

Enteropathogenicity of Dutch and German avian reoviruses in SPF white leghorn chickens and broilers

Investigations into the role of reovirus in the malabsorption syndrome

Contact Info

Product

Resources

About