Infectious Zika viral particles in breastmilk

Dupont‐Rouzeyrol, Myrielle; Biron, Antoine; O’Connor, Olivia; Huguon, Emilie; Descloux, Élodie

doi:10.1016/s0140-6736(16)00624-3

Cited by 210 publications

(197 citation statements)

References 4 publications

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“…The particles replicated in Vero cell culture, reaching 30,000,000 copies/mL. Results from the newborn blood sample were ambiguous and it is not clear whether the child developed the disease (60) .…”

Section: Zika Virus: Old and Newly Identified Transmission Modesmentioning

confidence: 99%

Zika virus: what do we know about the viral structure, mechanisms of transmission, and neurological outcomes?

Silva

Souza

2016

Rev. Soc. Bras. Med. Trop.

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The Zika virus epidemic that started in Brazil in 2014 has spread to >30 countries and territories in Latin America, leading to a rapid rise in the incidence of microcephalic newborns and adults with neurological complications. At the beginning of the outbreak, little was known about Zika virus morphology, genome structure, modes of transmission, and its potential to cause neurological malformations and disorders. With the advancement of basic science, discoveries of the mechanisms of strain variability, viral transfer to the fetus, and neurovirulence were published. These will certainly lead to the development of strategies to block vertical viral transmission, neuronal invasion, and pathogenesis in the near future. This paper reviews the current literature on Zika virus infections, with the aim of gaining a holistic insight into their etiology and pathogenesis. We discuss Zika virus history and epidemiology in Brazil, viral structure and taxonomy, old and newly identified transmission modes, and neurological consequences of infection.

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Section: Zika Virus: Old and Newly Identified Transmission Modesmentioning

confidence: 99%

Zika virus: what do we know about the viral structure, mechanisms of transmission, and neurological outcomes?

Silva

Souza

2016

Rev. Soc. Bras. Med. Trop.

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“…Transmission through breast milk has not been documented, although the breast milk of a woman contained infective Zika viral particles in high titer who became symptomatic with Zika virus infection on the day of delivery 23 . 5.4.…”

Section: Vertical Transmissionmentioning

confidence: 99%

Epidemiology, Diagnosis and Preventive Measures of Zika Virus Infection: A Review Update

Parveen

Begum

Sharmin

et al. 2017

Bangladesh J. Infect. Dis.

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The relation between ZIKV infection during pregnancy and microcephaly in neonate has been established by the Brazillian Ministry of Health. Therefore, more attention regarding control of Aedes mosquito is required. Since it transmits this disease, which has more disastrous consequences than dengue viral infection. Potentially effective methods of prevention that are focused on reducing infections among pregnant women include avoiding unnecessary travel to areas of ongoing Zika virus transmission, avoiding unprotected sexual contact with partners who are at risk for Zika virus infection. According to Institute of Epidemiology Disease Control and Reseaech (IEDCR) there is nothing to panic at this moment for Bangladesh, but they stressed on mosquito control, which is the only tool to prevent and fight off Zika virus. They however, could not mention how the virus came to Bangladesh. May be somebody brought it while travelling. There is good survillence and testing system to detect the disease in Bangladesh.

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“…La présence d'ARN viral Zika a été confirmée dans le sang des deux mères mais aussi des enfants, suggérant fortement une transmission périnatale [46]. Du virus réplicatif a également été mis en évidence dans du lait maternel d'une femme infectée en Nouvelle Calédonie [47]. Ces modes de transmission (périnatal et/ou par allaitement maternel) ont aussi été rapportés pour d'autres arbovirus tels que le CHIKV [48], le DENV [49] ou le WNV [50].…”

Section: Aedes Aegypti Aedes Albopictusunclassified

Le virus Zika

et al. 2016

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Infectious Zika viral particles in breastmilk

Abstract: Submissions should be made via our electronic submission system at http://ees.elsevier.com/ thelancet/

Cited by 210 publications

References 4 publications

Zika virus: what do we know about the viral structure, mechanisms of transmission, and neurological outcomes?

Zika virus: what do we know about the viral structure, mechanisms of transmission, and neurological outcomes?

Epidemiology, Diagnosis and Preventive Measures of Zika Virus Infection: A Review Update

Le virus Zika

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