The aim of this study was to determine the relative value of clinical, échocardiographie,
Doppler, and catheterization examinations in recognizing the
presence and estimating the severity of acute aortic regurgitation in critically
ill patients. Retrospective analyses of clinical, échocardiographie, Doppler,
and cardiac catheterization data were performed. Twenty-four acutely ill
patients with echo-Doppler evidence of acute severe aortic regurgitation who
either underwent aortic valve replacement (n = 21) or died and had autopsies
(n = 3) were studied. Clinically, acute severe regurgitation was diagnosed in
the presence of an early diastolic murmur accompanied by tachypnea, tachycardia,
and bilateral basilar rales. By echo-Doppler, acute severe aortic regurgitation
was diagnosed in the presence of early closure of the mitral valve on
the M-mode echocardiogram and an aortic regurgitation velocity half-time
< 280 ms by continuous-wave Doppler ultrasound. The sensitivity of the clinical
findings and noninvasive studies was assessed against invasive estimates
of regurgitation severity by aortography in 12 patients and ventricular sump
flow at the time of aortic valve replacement in 21 patients. By clinical examination,
aortic regurgitation was detected in 18 (75%) patients, but was considered
severe in only 12 (50%). M-mode echocardiography detected the presence
of aortic regurgitation in 12 patients, but premature closure of the mitral
valve was seen in only 6 (25%). Doppler studies detected the presence of aortic
regurgitation in all 24 patients, and Doppler half-time <280 ms accurately
predicted aortic regurgitation severity in all but 2 patients. The latter 2
patients had a markedly elevated left ventricular end-diastolic pressure and a
moderately severe rather than a severe aortic regurgitation by aortography.
Aortography added little to the information already obtained by Doppler
studies. Two patients died while waiting for aortography. Coronary angiography
detected associated coronary artery disease in 3 of the 12 patients. Clinically,
it is difficult to evaluate the severity of acute aortic regurgitation in the
critically ill. The continuous-wave Doppler half-time method permits noninvasive,
rapid detection and accurate estimation of aortic regurgitation severity.
Cardiac catheterization is recommended only when the noninvasive evaluation
is inconclusive or evaluation of the coronary anatomy is indicated.