Infektionsdiagnostik in der Pneumologie

Strassburg, A.; Dalhoff, K; Ewig, Santiago; Herth, Felix J.F.; Knobloch, J; Rohde, Gernot; Sahly, Hana M. El; Schaaf, Beate; Lange, Christoph

doi:10.1055/s-0029-1244120

Cited by 5 publications

(1 citation statement)

References 35 publications

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“…Während inhalierte Aspergillus-Konidien bei neutropenischen Patienten die unmittelbar lebensbedrohliche angioinvasive Aspergillose (IA) mit hämatogener Streuung und akutem Krankheitsbild hervorrufen können, sind sie bei immun-kompetenten Patienten lediglich als mögliches Allergen von pathologischer Bedeutung (z. B. bei der allergischen bronchopulmonalen Aspergillose [ABPA] oder der exogen allergischen Alveolitis) [27].…”

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Chronische pulmonale Aspergillose

Schweer

Wittersheim

Bangard

et al. 2014

Dtsch med Wochenschr

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Chronic pulmonary aspergillosis (CPA) is a rare complication in patients with either mild immunosuppression or various pulmonary diseases. Diagnosis and therapy are challenging because of unspecific symptoms like productive cough, weight loss, fever and haemoptysis. Differential diagnoses are manifold, and CPA is characterized by findings in chest CT and serologic proof of precipitins. Surgery is only recommended for simple aspergillomas. Recurrent prolonged courses of antifungal treatment yield satisfactory short-term outcome, but long-term prognosis is uncertain. We provide an overview of the literature and present four cases to illustrate disease diversity.

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unclassified

Chronische pulmonale Aspergillose

Schweer

Wittersheim

Bangard

et al. 2014

Dtsch med Wochenschr

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Erkrankungen Der Atmungsorgane

Jung¹,

Mayet²,

Mertens³

et al. 2020

Rationelle Diagnostik Und Therapie in Der Inneren Medizin

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Therapeutic approach to respiratory infections in lung transplantation

Clajus

Blasi

Welte

et al. 2015

Pulmonary Pharmacology & Therapeutics

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Lung transplant recipients (LTRs) are at life-long risk for infections and disseminated diseases owing to their immunocompromised state. Besides organ failure and sepsis, infection can trigger acute and chronic graft rejection which increases mortality. Medical prophylaxis and treatment are based on comprehensive diagnostic work-up including previous history of infection and airway colonisation to reduce long-term complications and mortality. Common bacterial pathogens include Pseudomonas and Staphylococcus, whilst Aspergillus and Cytomegalovirus (CMV) are respectively the commonest fungal and viral pathogens. Clinical symptoms can be various in lung transplant recipients presenting an asymptomatic to severe progress. Regular control of infection parameters, daily lung function testing and lifelong follow-up in a specialist transplant centre are mandatory for early detection of bacterial, viral and fungal infections. After transplantation each patient receives intensive training with rules of conduct concerning preventive behaviour and to recognize early signs of post transplant complications. Early detection of infection and complications are important goals to reduce major complications after lung transplantation.

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Infektionsdiagnostik in der Pneumologie

Cited by 5 publications

References 35 publications

Chronische pulmonale Aspergillose

Chronische pulmonale Aspergillose

Erkrankungen Der Atmungsorgane

Therapeutic approach to respiratory infections in lung transplantation

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