Mini implants have been researched extensively in terms of their efficiency, material used, and methods of accurate placement. When properly used,they might be a substitute method of anchorage preparation as compared toconventional molar anchorage and might reach alike or even superior results in certaincases.The present study aimed to evaluate and compare accuracy and stability of orthodontic temporary anchorage device with and without the use of Mini-implantplacement guiding device (MIG-20) in adults.Each patient underwent implant placement using both methods to have a similar oral environment for groups. Each case was treated in a split-mouth pattern to eliminateselection bias (to have the same baseline characteristics for both groups). Sideselection for that particular method was undertaken by using computer-generatedrandomization. So in all 2 groups were categorized. Mini-implant inserted by theconventional method (Control Group). Group II: Mini- Implant inserted by using MIG-20. Mini-implants were placed on both sides of the maxillary jaw between the 1 st molarand 2 nd premolar with the self-drilling manual method. Evaluation of clinical pictures, pre and post RVG and stability/mobility were done for each sample in both groupsusing AutoCAD software 2013.Out of 21 cases in Control group, it was observed that100% of cases in Control group had a vertically deviated mini-implant, which was statistically significant as compared to Study group, where 28.57% (6) cases demonstrated vertical deviation and 71.43 % (15) cases, where no deviation of miniimplantwas seen in vertical dimension when observed clinically. (p=0.0001, S). In71.43 % of cases, no significant variation was observed clinically in Study Group inmesiodistal dimension. (p=0.0001, S).The findings of the study substantiate the effectiveness of the 3-D Mini-Implant placement guide (MIG-20) when compared to the conventional method, inachieving a more accurate mesiodistal and vertical placement of mini implants.