“…Estimates of the timeline of species divergence support a version of the origins of inbreeding Lolium weeds in which L. persicum invaded early cultivated fields and differentiated into L. remotum in flax and L. temulentum in cereals (Fuller & Stevens, ). As the result of co‐selection for traits that constitute the cereal domestication syndrome, including self‐fertility, L. temulentum became established as a potent mimic weed 'which was to haunt European farmers until the late Middle Ages' (Mabey, )—an anthropophyte or what Fuller and Stevens () call a “domesticoid.” Archaeobotanical studies of Pre‐Pottery Neolithic sites, principally in the Eastern Mediterranean region, have consistently found remains of L. temulentum grains within cereal assemblages, and also in the preserved excreta of domesticated animals, dating as far back as 20,000 years BCE (Greenberg et al, ; Hartmann‐Shenkman, Kislev, Galili, Melamed, & Weiss, ; Kislev, ; Koromila et al, ; Kotzamani & Livarda, ; Snir et al, ; Weide, Riehl, Zeidi, & Conard, ). The human‐ L. temulentum relationship is an ancient one, and L. temulentum was clearly entering the food chain in the earliest human settlements on a similar basis to other weeds like wild oat and rye (Fuller & Stevens, ; Harlan & de Wet, ; Ladzinsky, ); but unlike these species, it was never developed into a secondary crop species in its own right ‐ possibly because of growing awareness of its toxic properties.…”