We prove that the boundary of the Hall-Littlewood t-deformation of the Gelfand-Tsetlin graph is parametrized by infinite integer signatures, extending results of Gorin [Gor12] and Cuenca [Cue18] on boundaries of related deformed Gelfand-Tsetlin graphs. In the special case when 1/t is a prime p we use this to recover results of Bufetov-Qiu [BQ17] and Assiotis [Ass20] on infinite p-adic random matrices, placing them in the general context of branching graphs derived from symmetric functions.Our methods rely on explicit formulas for certain skew Hall-Littlewood polynomials. As a separate corollary to these, we obtain a simple expression for the joint distribution of the cokernels of products A1, A2A1, A3A2A1, . . . of independent Haar-distributed matrices Ai over the p-adic integers Zp. This expression generalizes the explicit formula for the classical Cohen-Lenstra measure on abelian p-groups. Contents 1. Introduction 2. Hall-Littlewood polynomials 3. Principally specialized skew Hall-Littlewood polynomials 4. The t-deformed Gelfand-Tsetlin graph and its boundary 5. Infinite p-adic random matrices and corners 6. Ergodic decomposition of p-adic Hua measures. 7. Products of finite p-adic random matrices Appendix A. Commuting dynamics and projection to the boundary References