Inflammasome-Inhibiting Nanoligomers Are Neuroprotective against Space-Induced Pathology in Healthy and Diseased Three-Dimensional Human Motor and Prefrontal Cortex Brain Organoids
Sadhana Sharma,
Vincenzo S. Gilberto,
Jon Rask
et al.
Abstract:The microgravity and space environment has been linked
to deficits
in neuromuscular and cognitive capabilities, hypothesized to occur
due to accelerated aging and neurodegeneration in space. While the
specific mechanisms are still being investigated, spaceflight-associated
neuropathology is an important health risk to astronauts and space
tourists and is being actively investigated for the development of
appropriate countermeasures. However, such space-induced neuropathology
offers an opportunity for accelerat… Show more
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