Inflammation and central nervous system Lyme disease

Fallon, Brian A.; Levin, Elizabeth S.; Schweitzer, Pernilla J.; Hardesty, David E.

doi:10.1016/j.nbd.2009.11.016

Cited by 81 publications

(71 citation statements)

References 137 publications

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“…The most frequent clinical picture is that of encephalomyelitis [22]. All our studied cases showed medium encephalic involvement consisting in sleepiness, confusion, vertigo, transient incontinence, sensibility and balance disorders.…”

Section: Discussionmentioning

confidence: 62%

Serological, clinical and epidemiological aspects of Lyme borreliosis in Mures County, Romania

Ţilea¹,

Tripon²,

Voidăzan³

et al. 2014

Romanian Review of Laboratory Medicine

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Section: Discussionmentioning

confidence: 62%

Serological, clinical and epidemiological aspects of Lyme borreliosis in Mures County, Romania

Ţilea¹,

Tripon²,

Voidăzan³

et al. 2014

Romanian Review of Laboratory Medicine

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“…Clinical manifestations of neuroborreliosis can be meningitis, meningoradiculitis, encephalopathy and peripheral neuropathy 1. The clinical course of this patient could not be explained by neuroborreliosis; moreover, this was ruled out by examination of the cerebrospinal fluid.…”

Section: Discussionmentioning

confidence: 77%

Diagnostic pathway to amyotrophic lateral sclerosis (ALS): the significance of Babinski's sign in a unique patient and the necessity for a multidisciplinary approach

et al. 2013

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In this case report, we present a patient with rare diagnosis of amyotrophic lateral sclerosis (ALS). In this patient, four different neurological disorders were diagnosed in a short-time period of 8 months. The first three diagnoses, chronic low back and leg pain, a left frontal gemistocytic astrocytoma WHO grade 2 and suspected Lyme's disease, could not fully explain the signs of physical examination. Finally, the diagnosis of ALS could reduce these signs to the same denominator.

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“…Since chronic LNB is usually accompanied by fatigue and arthralgias, overlap with fibromyalgia exists. Described neuropsychiatric disorders secondary to LNB include depressive state (relatively frequent), mania, psychosis, dementia and obsessive-compulsive disorder 11 12. To our knowledge, the array of complaints of our patient without any neurological deficits has never been described before.…”

Section: Discussionmentioning

confidence: 79%

Misleading presentation of acute Lyme neuroborreliosis

2012

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A young man presented with recent-onset non-specific symptoms like headache, sleepiness and weight loss, interfering with normal daily life. Physical and biochemical irregularities were absent. Because extensive examination by neurologist and psychiatrist including brain imaging did not reveal any clues, the complaints were initially considered psychosomatic. As the symptoms deteriorated with ongoing weight loss, the patient was re-admitted to the hospital. Again, extensive additional investigation did not reveal any abnormalities. Because of previous exposition to the woods Lyme serology was determined. Surprisingly, it appeared to be a remarkable presentation of acute Lyme neuroborreliosis which was successfully treated with ceftriaxon. Clinicians must be aware of the fact that this severe illness can present without any typical symptoms.

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Inflammation and central nervous system Lyme disease

Cited by 81 publications

References 137 publications

Serological, clinical and epidemiological aspects of Lyme borreliosis in Mures County, Romania

Serological, clinical and epidemiological aspects of Lyme borreliosis in Mures County, Romania

Diagnostic pathway to amyotrophic lateral sclerosis (ALS): the significance of Babinski's sign in a unique patient and the necessity for a multidisciplinary approach

Misleading presentation of acute Lyme neuroborreliosis

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