2017
DOI: 10.5539/gjhs.v9n8p169
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Inflammation Mediators Related to Periodontal Disease and Pregnancy Outcomes: A Call for Quality of Antenatal Care While Promising Evidences Are Emerging

Abstract: Infections may play a significant role in the induction of births and prematurity. Periodontal disease could be a risk factor for pregnancy outcomes such as preterm birth, and low birth weight. Possible mechanisms of this relationship are the production of inflammatory mediators and cytokines like C-reactive protein (CRP), prostaglandin E2 (PGE2), matrix metalloproteinases, interleukin 1 (IL-1), IL-6, and tumor necrosis factor alfa (TNF-a); the translocation of periodontal pathogens to the feto-placental unit … Show more

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